Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. (Q36991072)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617754%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein (English)

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21 December 2019

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6

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21 December 2019

4

Thomas H Bugge

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21 December 2019

author name string

Manuel Yepes

1

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21 December 2019

Maria Sandkvist

2

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21 December 2019

Elizabeth G Moore

3

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21 December 2019

Dudley K Strickland

5

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21 December 2019

language of work or name

English

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publication date

1 November 2003

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Journal of Clinical Investigation

21 December 2019

published in

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21 December 2019

volume

112

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21 December 2019

issue

10

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21 December 2019

page(s)

1533-1540

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Protease-activated receptors in the cardiovascular system

21 December 2019

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Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats

29 September 2017

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Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent

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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

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29 September 2017

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Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator

29 September 2017

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29 September 2017

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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

29 September 2017

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A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier

29 September 2017

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29 September 2017

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Tissue plasminogen activator for acute ischemic stroke

29 September 2017

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The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist

29 September 2017

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Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

29 September 2017

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Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator

29 September 2017

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Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

29 September 2017

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Activation of protease-activated receptor-2 (PAR-2) elicits nitric oxide-dependent dilatation of the basilar artery in vivo

27 June 2018

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27 June 2018

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27 June 2018

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Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation

27 June 2018

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27 June 2018

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Cell Type-Specific Roles for Tissue Plasminogen Activator Released by Neurons or Microglia after Excitotoxic Injury

27 June 2018

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4 September 2018

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Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity

4 September 2018

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Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke

4 September 2018

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4 September 2018

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4 September 2018

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Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.

4 September 2018

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Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background

4 September 2018

1 reference

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Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning.

4 September 2018

1 reference

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Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

4 September 2018

1 reference

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Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis

4 September 2018

1 reference

12 December 2020

The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism

1 reference

12 December 2020

Storage and release of tissue plasminogen activator by sympathetic axons in resistance vessel walls

1 reference

12 December 2020

Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke

1 reference

12 December 2020

Proteolytic cascade enzymes increase in focal cerebral ischemia in rat

1 reference

12 December 2020

Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window

1 reference

12 December 2020

Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200319212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617754%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617754%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

14617754

1 reference