Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice (Q36993836)

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scientific article published on October 2008

Language	Label	Description	Also known as
English	Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice	scientific article published on October 2008

Statements

scholarly article

1 reference

Europe PubMed Central

17 August 2017

Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice (English)

1 reference

Europe PubMed Central

17 August 2017

type-1 diabetes

0 references

1 reference

based on heuristic

inferred from title

3

object named as

Roland Tisch

1 reference

Europe PubMed Central

17 August 2017

2

object named as

Bo Wang

1 reference

Europe PubMed Central

17 August 2017

1

object named as

Kevin S Goudy

1 reference

Europe PubMed Central

17 August 2017

publication date

1 October 2008

1 reference

Europe PubMed Central

17 August 2017

Clinical Immunology

1 reference

Europe PubMed Central

17 August 2017

129

1 reference

Europe PubMed Central

17 August 2017

1

1 reference

Europe PubMed Central

17 August 2017

49-57

1 reference

Europe PubMed Central

17 August 2017

Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Plasmid-based gene therapy of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Gene-based vaccines: recent technical and clinical advances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Intradermal or oral delivery of GAD-encoding genetic vaccines suppresses type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Particle-mediated DNA vaccination of mice, monkeys and men: looking beyond the dogma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

29 September 2017

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

27 June 2018

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

27 June 2018

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

4 September 2018

Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

4 September 2018

Antigen-based therapies using ignored determinants of beta cell antigens can more effectively inhibit late-stage autoimmune disease in diabetes-prone mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

4 September 2018

Increased nonobese diabetic Th1:Th2 (IFN-gamma:IL-4) ratio is CD4+ T cell intrinsic and independent of APC genetic background

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

4 September 2018

Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

4 September 2018

Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2593033

20 October 2018

DNA vaccination encoding glutamic acid decarboxylase can enhance insulitis and diabetes in correlation with a specific Th2/3 CD4 T cell response in non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA immunisation: altering the cellular localisation of expressed protein and the immunisation route allows manipulation of the immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene-gun biolistic immunization encoding glutamic acid decarboxylase: a model for studying Langerhans cell abnormalities and mimicry in the nonobese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICOS mediates the development of insulin-dependent diabetes mellitus in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18675592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CLIM.2008.06.001

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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0 references

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