Von Hippel-Lindau tumor suppressor gene loss in renal cell carcinoma promotes oncogenic epidermal growth factor receptor signaling via Akt-1 and MEK-1 (Q37001330)

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scientific article published on 16 January 2008

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English	Von Hippel-Lindau tumor suppressor gene loss in renal cell carcinoma promotes oncogenic epidermal growth factor receptor signaling via Akt-1 and MEK-1	scientific article published on 16 January 2008

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scholarly article

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2 January 2020

Von Hippel-Lindau tumor suppressor gene loss in renal cell carcinoma promotes oncogenic epidermal growth factor receptor signaling via Akt-1 and MEK-1 (English)

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2 January 2020

renal cell carcinoma

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based on heuristic

inferred from title

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Donald P. Bottaro

5

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2 January 2020

author name string

S Justin Lee

1

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2 January 2020

Jean-Baptiste Lattouf

2

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2 January 2020

Julie Xanthopoulos

3

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2 January 2020

W Marston Linehan

4

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2 January 2020

James R Vasselli

6

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2 January 2020

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publication date

16 January 2008

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2 January 2020

European Urology

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2 January 2020

54

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2 January 2020

4

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2 January 2020

845-853

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2 January 2020

Renal cell carcinoma guideline

1 reference

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The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells

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The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy

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29 September 2017

Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma

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Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics

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Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839.

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Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors.

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29 September 2017

The epidermal growth factor receptor as a target for colorectal cancer therapy

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29 September 2017

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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29 September 2017

The erbB family: targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors

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Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

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29 September 2017

LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis

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29 September 2017

Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596938

29 September 2017

Targeting epidermal growth factor receptor--are we missing the mark?

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29 September 2017

Early Growth Response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia

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29 September 2017

Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596938

29 September 2017

Signaling by distinct classes of phosphoinositide 3-kinases

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29 September 2017

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

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29 September 2017

Tumour suppression by the human von Hippel-Lindau gene product

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29 September 2017

Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma.

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27 June 2018

Renal-Cell Carcinoma

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4 September 2018

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Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival

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4 September 2018

Phase II trial of ZD1839 (IRESSA) in patients with advanced renal cell carcinoma

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4 September 2018

Phase II trial of antiepidermal growth factor receptor antibody C225 in patients with advanced renal cell carcinoma.

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4 September 2018

Requirement for the von Hippel-Lindau tumor suppressor gene for functional epidermal growth factor receptor blockade by monoclonal antibody C225 in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18243508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18243508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concomitant overexpression of the EGFR and erbB-2 genes in renal cell carcinoma (RCC) is correlated with dedifferentiation and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18243508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18243508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EURURO.2008.01.010

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2 January 2020

1 reference

Europe PubMed Central

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2 January 2020

1 reference

Europe PubMed Central

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2 January 2020

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