Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases (Q37006166)

17 August 2017

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title

Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases (English)

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inflammatory bowel diseases

17 August 2017

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Luca Antonioli

1

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17 August 2017

Matteo Fornai

2

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17 August 2017

Rocchina Colucci

3

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17 August 2017

Narcisa Ghisu

4

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17 August 2017

Marco Tuccori

5

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17 August 2017

Mario Del Tacca

6

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17 August 2017

Corrado Blandizzi

7

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17 August 2017

1 April 2008

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Inflammatory Bowel Diseases

17 August 2017

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17 August 2017

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17 August 2017

566-574

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17 August 2017

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Biologic therapy for inflammatory bowel disease.

17 August 2017

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Structure and function of adenosine receptors and their genes.

21 January 2018

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Shaping of monocyte and macrophage function by adenosine receptors

21 January 2018

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Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system

21 January 2018

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Adenosine A1 receptor blockade reverses experimental postoperative ileus in rat colon.

21 January 2018

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A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis.

21 January 2018

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Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes

21 January 2018

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Adenosine uptake inhibitors

21 January 2018

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Physiological roles for ecto-5'-nucleotidase (CD73).

21 January 2018

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Adenosine in the central nervous system: release mechanisms and extracellular concentrations

21 January 2018

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Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation.

21 January 2018

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Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

21 January 2018

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The 'danger' sensors that STOP the immune response: the A2 adenosine receptors?

21 January 2018

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Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors.

21 January 2018

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Analysis of A2a receptor-deficient mice reveals no significant compensatory increases in the expression of A2b, A1, and A3 adenosine receptors in lymphoid organs

21 January 2018

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Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, [3H]MRE 2029-F20.

21 January 2018

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Adenosine A2A agonists in development for the treatment of inflammation

21 January 2018

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Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

21 January 2018

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Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation

21 January 2018

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The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules

21 January 2018

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Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes

21 January 2018

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

21 January 2018

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Cell biology. Purinergic chemotaxis

21 January 2018

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Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism

21 January 2018

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A(3) adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study

21 January 2018

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Endogenous adenosine regulates neutrophil pro-inflammatory activities by cyclic AMP-dependent accelerated clearance of cytosolic calcium.

21 January 2018

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Regulation of adenosine receptor subtypes during cultivation of human monocytes: role of receptors in preventing lipopolysaccharide-triggered respiratory burst

21 January 2018

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Specific inhibition of nuclear factor-kappaB-dependent inflammatory responses by cell type-specific mechanisms upon A2A adenosine receptor gene transfer

21 January 2018

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Endothelial cell cytoprotection induced in vitro by allo- or xenoreactive antibodies is mediated by signaling through adenosine A2 receptors

21 January 2018

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Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms

21 January 2018

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Activation of the adenosine A3 receptor in RAW 264.7 cells inhibits lipopolysaccharide-stimulated tumor necrosis factor-alpha release by reducing calcium-dependent activation of nuclear factor-kappaB and extracellular signal-regulated kinase 1/2.

21 January 2018

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Adenosine: an endogenous regulator of innate immunity

21 January 2018

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Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells

21 January 2018

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CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse.

21 January 2018

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Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106.

21 January 2018

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Points of control in inflammation

21 January 2018

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Myeloperoxidase and adenosine-deaminase levels in the pleural fluid leakage induced by carrageenan in the mouse model of pleurisy

21 January 2018

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Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses

21 January 2018

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Rabbit chronic ileitis leads to up-regulation of adenosine A1/A3 gene products, oxidative stress, and immune modulation

21 January 2018

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Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.

21 January 2018

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Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide.

21 January 2018

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Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease

21 January 2018

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TNF-alpha upregulates adenosine 2b (A2b) receptor expression and signaling in intestinal epithelial cells: a basis for A2bR overexpression in colitis

21 January 2018

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ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis.

21 January 2018

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Immune dysfunction in inflammatory bowel disease

21 January 2018

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Inflammatory bowel disease: cause and immunobiology

21 January 2018

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Immunopathogenesis of IBD: insufficient suppressor function in the gut?

21 January 2018

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Antioxidants as novel therapy in a murine model of colitis

21 January 2018

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Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells

21 January 2018

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The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

21 January 2018

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Molecular therapeutics. Methotrexate and its mechanism of action

21 January 2018

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Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides

21 January 2018

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Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis

21 January 2018

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The adenosine A2A receptor agonist CGS 21680 fails to ameliorate the course of dextran sulphate-induced colitis in mice

21 January 2018

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Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts

21 January 2018

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Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.

21 January 2018

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Changes in enteric neural circuitry and smooth muscle in the inflamed and infected gut.

21 January 2018

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Neuroimmune and epithelial interactions in intestinal inflammation.

21 January 2018

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Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum

21 January 2018

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Dual effects of adenosine on acetylcholine release from myenteric motoneurons are mediated by junctional facilitatory A(2A) and extrajunctional inhibitory A(1) receptors.

21 January 2018

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Animal models for the study of adenosine receptor function.

21 January 2018

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Molecular identification and pharmacological characterization of adenosine receptors in the guinea-pig colon

21 January 2018

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Antagonist pharmacology of adenosine A2B receptors from rat, guinea pig and dog.

21 January 2018

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Alteration of the purinergic modulation of enteric neurotransmission in the mouse ileum during chronic intestinal inflammation

21 January 2018

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Characterization and tissue location of the neural adenosine receptor in the rat ileum

21 January 2018

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Luminal adenosine stimulates chloride secretion through A1 receptor in mouse jejunum

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IBD.20316

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17 August 2017

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