Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein (Q37013499)

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scientific article published on 10 March 2016

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English	Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein	scientific article published on 10 March 2016

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scholarly article

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Europe PubMed Central

17 August 2017

Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein (English)

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Europe PubMed Central

17 August 2017

1 reference

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Richard L Dunbar

14

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1 June 2020

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Gissette Reyes-Soffer

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John S Millar

2

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Colleen Ngai

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Patricia Jumes

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Ellie Coromilas

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Bela Asztalos

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Amy O Johnson-Levonas

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John A Wagner

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Daniel S Donovan

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Wahida Karmally

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Rajasekhar Ramakrishnan

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Stephen Holleran

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Tiffany Thomas

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Emil M deGoma

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Hashmi Rafeek

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Amanda L Baer

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Yang Liu

18

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Michael E Lassman

19

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David E Gutstein

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1 June 2020

Daniel J Rader

21

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Henry N Ginsberg

22

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1 June 2020

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publication date

10 March 2016

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17 August 2017

Arteriosclerosis, Thrombosis, and Vascular Biology

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1 June 2020

36

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1 June 2020

5

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1 June 2020

994-1002

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1 June 2020

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

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29 September 2017

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

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29 September 2017

Future of cholesteryl ester transfer protein inhibitors

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29 September 2017

In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption

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29 September 2017

Effects of cholesteryl ester transfer protein inhibitors on human lipoprotein metabolism: why have they failed in lowering coronary heart disease risk?

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29 September 2017

Effects of dalcetrapib in patients with a recent acute coronary syndrome

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29 September 2017

Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib

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29 September 2017

Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial.

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Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

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Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

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Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels

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Major lipids, apolipoproteins, and risk of vascular disease

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Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients

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Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

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Effects of torcetrapib in patients at high risk for coronary events

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Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux

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Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.

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Pharmacological modulation of cholesteryl ester transfer protein, a new therapeutic target in atherogenic dyslipidemia

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The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor

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Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men.

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Increased plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in subjects with low levels of high density lipoprotein cholesterol

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911016

29 September 2017

Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency

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29 September 2017

Cholesteryl ester transfer protein: its role in plasma lipid transport

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Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia

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29 September 2017

Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences

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29 September 2017

Characterization of high-density apolipoprotein particles A-I and A-I:A-II isolated from humans with cholesteryl ester transfer protein deficiency

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Safety of anacetrapib in patients with or at high risk for coronary heart disease

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27 June 2018

Biochemical characterization of cholesteryl ester transfer protein inhibitors

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27 June 2018

Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib

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27 June 2018

Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism

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27 June 2018

Assessment of the clinical effects of cholesteryl ester transfer protein inhibition with evacetrapib in patients at high-risk for vascular outcomes: Rationale and design of the ACCELERATE trial.

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4 September 2018

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1 reference

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4 September 2018

Apolipoprotein composition of HDL in cholesteryl ester transfer protein deficiency

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4 September 2018

Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size. Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distri

1 reference

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4 September 2018

Two-dimensional electrophoresis of plasma lipoproteins: recognition of new apo A-I-containing subpopulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/26966279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of ApoA-I-containing HDL subpopulations in patients with coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26966279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of apolipoprotein A-I turnover in subjects with reduced concentrations of plasma high density lipoprotein cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/26966279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26966279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/ATVBAHA.115.306680

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Europe PubMed Central

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1 June 2020

release_vwe2jzaqqfaf3bjc5ewezg2scq

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24 November 2022

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mapped directly with Wikidata item

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Europe PubMed Central

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1 June 2020

1 reference

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1 June 2020

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