Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS. (Q37015510)

17 August 2017

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title

Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS. (English)

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17 August 2017

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1

Stephen Dewhurst

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17 August 2017

4

Howard E Gendelman

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17 August 2017

2

Sanjay B Maggirwar

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17 August 2017

Giovanni Schifitto

3

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PubMed ID

18040831

17 August 2017

Harris A Gelbard

series ordinal

5

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17 August 2017

16 December 2006

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Journal of Neuroimmune Pharmacology

17 August 2017

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17 August 2017

2

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17 August 2017

1

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17 August 2017

93-96

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https://scigraph.springernature.com/pub.10.1007/s11481-006-9051-1

17 August 2017

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cites work

Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia

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Reduced brain N-acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus-seropositive individuals: in vivo 1H magnetic resonance spectroscopic imaging

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-006-9051-1

Clinical and spectroscopic improvement in HIV-associated cognitive impairment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-006-9051-1

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

21 January 2018

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12 December 2020

Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons

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Interaction of synaptic scaffolding molecule and Beta -catenin.

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Hypertonic Stress Activates Glycogen Synthase Kinase 3β-mediated Apoptosis of Renal Medullary Interstitial Cells, Suppressing an NFκB-driven Cyclooxygenase-2-dependent Survival Pathway

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HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity

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12 December 2020

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Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling

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12 December 2020

Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.

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Wnts and TGF beta in synaptogenesis: old friends signalling at new places

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Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons

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Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

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Valproic acid does not affect markers of human immunodeficiency virus disease progression

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Lithium improves HIV-associated neurocognitive impairment

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Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report.

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Effects of valproic acid coadministration on plasma efavirenz and lopinavir concentrations in human immunodeficiency virus-infected adults.

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease

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Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

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Neurodevelopmental/neuroradiologic recovery of a child infected with HIV after treatment with combination antiretroviral therapy using the HIV-specific protease inhibitor ritonavir

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Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia

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Lithium ameliorates HIV-gp120-mediated neurotoxicity

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Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus-infected monkeys

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Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function

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12 December 2020

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

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12 December 2020

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

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12 December 2020

10.1007/S11481-006-9051-1

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

18040831