Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis (Q37018913)

17 August 2017

Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis (English)

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17 August 2017

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13

Eric S Lander

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17 August 2017

Karl W Broman

12

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Mark Joseph Daly

11

object named as

Mark J Daly

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17 August 2017

Hayden-William Courtland

7

object named as

Hayden-William Courtland

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17 August 2017

Haifeng Shao

1

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17 August 2017

Lindsay C Burrage

2

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17 August 2017

David S Sinasac

3

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17 August 2017

Annie E Hill

4

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17 August 2017

Sheila R Ernest

5

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17 August 2017

William O'Brien

6

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17 August 2017

Karl J Jepsen

8

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17 August 2017

Andrew Kirby

9

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17 August 2017

E J Kulbokas

10

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17 August 2017

Joseph H Nadeau

14

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17 August 2017

language of work or name

English

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publication date

9 December 2008

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17 August 2017

5

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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17 August 2017

105

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17 August 2017

50

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17 August 2017

19910-19914

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Data and theory point to mainly additive genetic variance for complex traits

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

A HapMap harvest of insights into the genetics of common disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Genome-wide association analysis identifies 20 loci that influence adult height

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Many sequence variants affecting diversity of adult human height

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Identification of ten loci associated with height highlights new biological pathways in human growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

The road to genome-wide association studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Genetic basis of proteome variation in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Attainment of Quasi Linkage Equilibrium When Gene Frequencies Are Changing by Natural Selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

29 September 2017

The genetics of health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Strategies for mapping and cloning quantitative trait genes in rodents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

The landscape of genetic complexity across 5,700 gene expression traits in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

R/qtl: QTL mapping in experimental crosses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

The genetic architecture of quantitative traits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Modifier genes in mice and humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Principles for the buffering of genetic variation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Analysing complex genetic traits with chromosome substitution strains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Mapping mendelian factors underlying quantitative traits using RFLP linkage maps

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Physiogenomic resources for rat models of heart, lung and blood disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Epistasis: too often neglected in complex trait studies?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Little epistasis for anxiety-related measures in the DeFries strains of laboratory mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Genetic dissection of complex traits with chromosome substitution strains of mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Dissecting the architecture of a quantitative trait locus in yeast

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2604967

Genome-wide genetic association of complex traits in heterogeneous stock mice

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0810388105

Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19066216

12 December 2020

inferred from PubMed ID database lookup

Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19066216

12 December 2020

inferred from PubMed ID database lookup

Gene expression analysis of mouse chromosome substitution strains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19066216

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0810388105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

19066216

1 reference