Novel soluble Flt-1 isoforms in plasma and cultured placental explants from normotensive pregnant and preeclamptic women. (Q37024446)

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17 January 2020

title

Novel soluble Flt-1 isoforms in plasma and cultured placental explants from normotensive pregnant and preeclamptic women (English)

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17 January 2020

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Frauke von Versen-Höynck

5

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17 January 2020

author name string

A Rajakumar

1

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17 January 2020

R W Powers

2

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17 January 2020

C A Hubel

3

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17 January 2020

E Shibata

4

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17 January 2020

D Plymire

6

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17 January 2020

A Jeyabalan

7

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17 January 2020

publication date

17 November 2008

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17 January 2020

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17 January 2020

volume

30

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17 January 2020

page(s)

25-34

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17 January 2020

issue

1

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Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling

17 January 2020

cites work

1 reference

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29 September 2017

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Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies

29 September 2017

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Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta.

29 September 2017

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Thrombin regulates soluble fms-like tyrosine kinase-1 (sFlt-1) expression in first trimester decidua: implications for preeclampsia

29 September 2017

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Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy

29 September 2017

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Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae

29 September 2017

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Post-transcriptional control of expression of sFlt-1, an endogenous inhibitor of vascular endothelial growth factor

29 September 2017

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Cytotrophoblasts up-regulate soluble fms-like tyrosine kinase-1 expression under reduced oxygen: an implication for the placental vascular development and the pathophysiology of preeclampsia

29 September 2017

1 reference

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Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy

29 September 2017

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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

29 September 2017

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Structure and function of VEGF/VEGF-receptor system involved in angiogenesis

29 September 2017

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Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen--a review.

29 September 2017

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Expression and localization of membrane type matrix metalloproteinase-1 (MT1-MMP) in trophoblast cells of cultured mouse blastocysts and ectoplacental cones

29 September 2017

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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

29 September 2017

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Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

29 September 2017

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Molecular evidence of placental hypoxia in preeclampsia.

29 September 2017

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Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues.

27 June 2018

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A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia

27 June 2018

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Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.

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Increased chymotrypsin-like protease (chymase) expression and activity in placentas from women with preeclampsia.

4 September 2018

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Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women.

4 September 2018

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Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta.

4 September 2018

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Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia.

4 September 2018

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4 September 2018

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The fourth immunoglobulin-like loop in the extracellular domain of FLT-1, a VEGF receptor, includes a major heparin-binding site.

4 September 2018

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4 September 2018

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Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1

4 September 2018

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Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts

20 October 2018

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12 December 2020

Impaired oxygen-dependent reduction of HIF-1alpha and -2alpha proteins in pre-eclamptic placentae

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12 December 2020

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

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12 December 2020

Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

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12 December 2020

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

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12 December 2020

Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension

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12 December 2020

Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression

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12 December 2020

Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors

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12 December 2020

10.1016/J.PLACENTA.2008.10.006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010535%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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17 January 2020

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