The role of exosomes in the processing of proteins associated with neurodegenerative diseases (Q37026739)

17 August 2017

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title

The role of exosomes in the processing of proteins associated with neurodegenerative diseases (English)

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17 August 2017

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Laura J Vella

1

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17 August 2017

Robyn A Sharples

2

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17 August 2017

Rebecca M Nisbet

3

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17 August 2017

Roberto Cappai

4

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17 August 2017

Andrew F Hill

5

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17 August 2017

7 December 2007

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European Biophysics Journal

17 August 2017

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17 August 2017

37

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17 August 2017

3

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17 August 2017

323-332

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https://scigraph.springernature.com/pub.10.1007/s00249-007-0246-z

17 August 2017

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TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex

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https://api.crossref.org/works/10.1007%2FS00249-007-0246-Z

Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface

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Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment

21 January 2018

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Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00249-007-0246-Z

Amyloid beta-protein and the genetics of Alzheimer's disease

21 January 2018

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Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00249-007-0246-Z

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00249-007-0246-Z

Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00249-007-0246-Z

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

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12 December 2020

Cellular and subcellular morphological localization of normal prion protein in rodent cerebellum

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12 December 2020

Asymmetric distribution of phospholipids in the membrane of vesicles released during in vitro maturation of guinea pig reticulocytes: evidence precluding a role for "aminophospholipid translocase".

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12 December 2020

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

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12 December 2020

Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma.

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12 December 2020

Cellular prion protein is released on exosomes from activated platelets

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12 December 2020

Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection

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12 December 2020

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

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12 December 2020

Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.

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12 December 2020

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming

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12 December 2020

Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity.

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12 December 2020

Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)

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12 December 2020

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

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12 December 2020

Prion protein is secreted in soluble forms in the epididymal fluid and proteolytically processed and transported in seminal plasma.

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12 December 2020

Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells

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12 December 2020

Exosome secretion: the art of reutilizing nonrecycled proteins?

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12 December 2020

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes

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12 December 2020

A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells

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12 December 2020

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

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12 December 2020

Trafficking of prion proteins through a caveolae-mediated endosomal pathway

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12 December 2020

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

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12 December 2020

Identification and proteomic profiling of exosomes in human urine

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12 December 2020

Exosomes are released by cultured cortical neurones.

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12 December 2020

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

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12 December 2020

The prion protein and lipid rafts

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12 December 2020

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

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12 December 2020

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

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12 December 2020

Cells release prions in association with exosomes

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12 December 2020

Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

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12 December 2020

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

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12 December 2020

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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12 December 2020

The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain

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12 December 2020

Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking

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12 December 2020

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

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12 December 2020

Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases

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12 December 2020

Intercellular transfer of the cellular prion protein

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12 December 2020

Tumor-derived exosomes: a new source of tumor rejection antigens

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12 December 2020

Exosomes: a bubble ride for prions?

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12 December 2020

Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection1

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12 December 2020

Lipid rafts and HIV-1: from viral entry to assembly of progeny virions.

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12 December 2020

Characterization of the Properties and Trafficking of an Anchorless Form of the Prion Protein

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12 December 2020

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

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12 December 2020

Induction of Tolerance by Exosomes and Short-Term Immunosuppression in a Fully MHC-Mismatched Rat Cardiac Allograft Model

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12 December 2020

Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res

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12 December 2020

Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors

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12 December 2020

Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease

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12 December 2020

Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis

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12 December 2020

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

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12 December 2020

Malignant effusions and immunogenic tumour-derived exosomes

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12 December 2020

Role of exosomes in sperm maturation during the transit along the male reproductive tract

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12 December 2020

Transfer of scrapie prion infectivity by cell contact in culture

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12 December 2020

Evidence That HIV Budding in Primary Macrophages Occurs through the Exosome Release Pathway

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12 December 2020

Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

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12 December 2020

Exosomes bearing HLA-G are released by melanoma cells.

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12 December 2020

Exosomes: composition, biogenesis and function

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12 December 2020

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

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12 December 2020

Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation

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12 December 2020

The exosome and RNA quality control in the nucleus

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12 December 2020

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

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12 December 2020

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

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12 December 2020

Compartmentalization of prion isoforms within the reproductive tract of the ram.

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12 December 2020

Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4

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12 December 2020

Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

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12 December 2020

In vitro methods in the study of viral and prion permeability across the blood-brain barrier

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12 December 2020

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

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12 December 2020

Role of exosomes in immune regulation

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12 December 2020

The Trojan exosome hypothesis

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12 December 2020

Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

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12 December 2020

Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells

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12 December 2020

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

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12 December 2020

Exosomal-like vesicles are present in human blood plasma

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12 December 2020

Cytosolic prion protein in neurons.

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12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

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12 December 2020

Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during In vitro maturation of reticulocytes

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12 December 2020

Intestinal epithelial cells secrete exosome-like vesicles

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12 December 2020

Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid

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12 December 2020

Lipid raft-associated protein sorting in exosomes.

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12 December 2020

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

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12 December 2020

Retrovirus infection strongly enhances scrapie infectivity release in cell culture

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12 December 2020

Induction of heat shock proteins in B-cell exosomes.

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12 December 2020

A protein's final ESCRT.

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12 December 2020

Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice.

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12 December 2020

Exosomes: endosomal-derived vesicles shipping extracellular messages

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12 December 2020

Novel proteinaceous infectious particles cause scrapie

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12 December 2020

Late endosomes: sorting and partitioning in multivesicular bodies.

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12 December 2020

A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

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12 December 2020

Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes

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12 December 2020

Presenilin/gamma-secretase activity regulates protein clearance from the endocytic recycling compartment.

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12 December 2020

Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies

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12 December 2020

Surface anchorage of superantigen SEA promotes induction of specific antitumor immune response by tumor-derived exosomes

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12 December 2020

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

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12 December 2020

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

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12 December 2020

Prions and exosomes: from PrPc trafficking to PrPsc propagation

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12 December 2020

Detection of soluble forms of the beta-amyloid precursor protein in human plasma.

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12 December 2020

Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses

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12 December 2020

The cellular isoform of the prion protein, PrPc, is associated with caveolae in mouse neuroblastoma (N2a) cells

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12 December 2020

Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins

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12 December 2020

Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes

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12 December 2020

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.

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12 December 2020

Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis

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12 December 2020

10.1007/S00249-007-0246-Z

Identifiers

DOI

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17 August 2017

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