Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes (Q37029553)

17 August 2017

1 reference

title

Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes (English)

1 reference

17 August 2017

0 references

Stephanie J Harris

1

0 references

Stephen G Ward

object named as

Stephen G Ward

series ordinal

4

0 references

author name string

Richard V Parry

series ordinal

2

1 reference

PubMed ID

18073217

17 August 2017

John Westwick

series ordinal

3

1 reference

PubMed ID

18073217

17 August 2017

language of work or name

English

0 references

publication date

10 December 2007

1 reference

Journal of Biological Chemistry

17 August 2017

5

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

17 August 2017

283

1 reference

17 August 2017

5

1 reference

17 August 2017

2465-2469

1 reference

Synthesis and function of 3-phosphorylated inositol lipids

17 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the g

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphoinositide 3-kinases in T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphoinositide 3-kinase: diverse roles in immune cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) reduces vascular endothelial growth factor expression in allergen-induced airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

The role of SHIP in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

T lymphocytes on the move: chemokines, PI 3-kinase and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Navigating signaling networks: chemotaxis in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphoinositide phosphatases in a network of signalling reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

A novel mode of action for a microbial-derived immunotoxin: the cytolethal distending toxin subunit B exhibits phosphatidylinositol 3,4,5-triphosphate phosphatase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Measles virus induces expression of SIP110, a constitutively membrane clustered lipid phosphatase, which inhibits T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Measles virus interacts with and alters signal transduction in T-cell lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

The PI3K inhibitor arsenal: choose your weapon!

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

Cloning of the genomic locus of mouse SH2 containing inositol 5-phosphatase (SHIP) and a novel 110-kDa splice isoform, SHIPdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R700044200

21 January 2018

Identifiers

DOI

10.1074/JBC.R700044200

1 reference

17 August 2017

1 reference

PubMed ID

18073217