Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses. (Q37036545)

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scientific article published on 13 May 2013

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English	Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.	scientific article published on 13 May 2013

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1 March 2020

Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses (English)

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1 March 2020

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John D Williams

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Gloria Komazin-Meredith

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Atiyya R Khan

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Nathan B Price

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Geraldine M Jefferson

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Emma A Harden

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Caroll B Hartline

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Norton P Peet

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Terry L Bowlin

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13 May 2013

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1 March 2020

Antimicrobial Agents and Chemotherapy

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3518-3527

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1 March 2020

Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides

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9 September 2017

Progress in the development of new therapies for herpesvirus infections

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9 September 2017

Antiviral Drug Resistance of Human Cytomegalovirus

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Emerging viruses in transplantation

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L-valine ester of cyclopropavir: a new antiviral prodrug.

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Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides

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9 September 2017

Antiviral therapy for herpesvirus central nervous system infections: neonatal herpes simplex virus infection, herpes simplex encephalitis, and congenital cytomegalovirus infection

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Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.

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(Z)- and (E)-2-(1,2-dihydroxyethyl)methylenecyclopropane analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, absolute configuration, and antiviral activity.

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Immunocompromised hosts: perspectives in the treatment and prophylaxis of cytomegalovirus disease in solid-organ transplant recipients

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Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine

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9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1

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Synthesis of Methylenecyclopropane Analogues of Antiviral Nucleoside Phosphonates

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Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections

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Recurrent antiviral-resistant genital herpes in an immunocompetent patient

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9 September 2017

In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication

1 reference

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9 September 2017

Oral activity of a methylenecyclopropane analog, cyclopropavir, in animal models for cytomegalovirus infections

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Herpes simplex virus resistance to antiviral drugs

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Antiviral therapy for varicella and herpes zoster

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9 September 2017

Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells

1 reference

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In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections

1 reference

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Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides

1 reference

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29 September 2017

Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity

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Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro

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Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus

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27 June 2018

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1 reference

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10.1128/AAC.00429-13

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1 March 2020

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