Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors (Q37037058)

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scientific article published on December 2007

Language	Label	Description	Also known as
English	Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors	scientific article published on December 2007

Statements

scholarly article

1 reference

Europe PubMed Central

17 August 2017

Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors (English)

1 reference

Europe PubMed Central

17 August 2017

0 references

author name string

Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group

1

1 reference

Europe PubMed Central

17 August 2017

language of work or name

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publication date

1 December 2007

1 reference

Europe PubMed Central

17 August 2017

Genetics in Medicine

1 reference

Europe PubMed Central

17 August 2017

9

1 reference

Europe PubMed Central

17 August 2017

12

1 reference

Europe PubMed Central

17 August 2017

819-825

1 reference

Europe PubMed Central

17 August 2017

https://scigraph.springernature.com/pub.10.1097/gim.0b013e31815bf9a3

0 references

Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Pharmacogenetics of antidepressant medication intolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Characterization of the 16+9 kb and 30+9 kb CYP2D6 XbaI haplotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

29 September 2017

A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

27 June 2018

Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of human cytochrome P450 CYP2D6 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

27 June 2018

Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

27 June 2018

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

27 June 2018

The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in japanese depressed patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Breastfeeding during maternal antidepressant treatment with serotonin reuptake inhibitors: infant exposure, clinical symptoms, and cytochrome p450 genotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Effects of dosage and CYP2D6-mutated allele on plasma concentration of paroxetine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Cytochrome p450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Polymorphisms in the CYP 2D6 gene: association with plasma concentrations of fluoxetine and paroxetine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Optimized Strategy for Rapid Cytochrome P450 2D6 Genotyping by Real-Time Long PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Pharmacokinetics of citalopram in relation to genetic polymorphism of CYP2C19.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Relationship between clinical effects of fluvoxamine and the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

CYP2D6*10 alleles do not determine plasma fluvoxamine concentration/dose ratio in Japanese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

A prospective study of 86 new patients with social anxiety disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Concentrations of the enantiomers of fluoxetine and norfluoxetine after multiple doses of fluoxetine in cytochrome P4502D6 poor and extensive metabolizers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

4 September 2018

Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population

2 references

https://api.crossref.org/works/10.1097%2FGIM.0B013E31815BF9A3

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743615

20 October 2018

Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequencing of a new non-functional CYP2D6 allele: deletion of T1795 in exon 3 generates a premature stop codon

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid detection of CYP2C18 genotypes by real-time fluorescence polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and reliable method for cytochrome P450 2D6 genotyping

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paroxetine Steady-State Plasma Concentration in Relation to CYP2D6 Genotype in Extensive Metabolizers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of paroxetine disposition to metoprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rare G2061 insertion affecting the open reading frame of CYP2D6 and responsible for the poor metabolizer phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of CYP2D6 gene copy number by pyrosequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/18091431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/GIM.0B013E31815BF9A3

1 reference

Europe PubMed Central

17 August 2017

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0 references

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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