Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration (Q37038075)

17 August 2017

1 reference

title

Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration (English)

1 reference

17 August 2017

0 references

J Kelley Bentley

1

1 reference

PMCID

2645305

17 August 2017

Marc B Hershenson

series ordinal

2

1 reference

17 August 2017

1 January 2008

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Proceedings of the American Thoracic Society

17 August 2017

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17 August 2017

5

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17 August 2017

1

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17 August 2017

89-96

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Human bronchial fibroblasts exhibit a mesenchymal stem cell phenotype and multilineage differentiating potentialities

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Prolonged allergen challenge in mice leads to persistent airway remodelling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Expression and effects of cardiotrophin-1 (CT-1) in human airway smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Mitogenic signaling pathways in airway smooth muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

IGFBP-3 mediates TGF-beta1-induced cell growth in human airway smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Markers of airway smooth muscle cell phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Cell cycle versus density dependence of smooth muscle alpha actin expression in cultured rat aortic smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Comparison of human bronchiolar smooth muscle responsiveness in vitro with histological signs of inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Pharmacology of Airway Smooth Muscle in Chronic Obstructive Pulmonary Disease in Asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Transforming growth factor-beta induces airway smooth muscle hypertrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Airway smooth muscle cell proliferation is increased in asthma

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Muscle and Mucous Gland Size in the Major Bronchi of Patients with Chronic Bronchitis, Asthma, and Asthmatic Bronchitis1–3

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Cardiotrophin-1 alters airway smooth muscle structure and mechanical properties in airway explants

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Resolution of allergic airways inflammation but persistence of airway smooth muscle proliferation after repeated allergen exposures.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Relationship of airway wall thickness to airway sensitivity and airway reactivity in asthma

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Airway structural alterations selectively associated with severe asthma.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Repeated allergen inhalation induces phenotypic modulation of smooth muscle in bronchioles of sensitized rats.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Increases in collagen type I synthesis in asthma: the role of eosinophils and transforming growth factor-beta

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Tryptase's potent mitogenic effects in human airway smooth muscle cells are via nonproteolytic actions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in primary tracheal myocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Serum deprivation induces a unique hypercontractile phenotype of cultured smooth muscle cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Functional significance of increased airway smooth muscle in asthma and COPD.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Pulmonary arterial smooth muscle contractility in hypoxia-induced pulmonary hypertension.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

alpha-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645305

p21-activated kinase 1 participates in tracheal smooth muscle cell migration by signaling to p38 Mapk

4 December 2018

1 reference

12 December 2020

Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study

1 reference

12 December 2020

Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity

1 reference

12 December 2020

Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells

1 reference

12 December 2020

A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration

1 reference

12 December 2020

Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration

1 reference

12 December 2020

CCR3 expression and function in asthmatic airway smooth muscle cells

1 reference

12 December 2020

Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells

1 reference

12 December 2020

Lung cells from neonates show a mesenchymal stem cell phenotype

1 reference

12 December 2020

Quantitative structural alterations in long-standing allergic asthma

1 reference

12 December 2020

The mechanics of airway narrowing in asthma

1 reference

12 December 2020

A human airway smooth muscle cell line that retains physiological responsiveness

1 reference

12 December 2020

Hyperreactive site in the airway tree of asthmatic patients revealed by thickening of bronchial muscles. A morphometric study

1 reference

12 December 2020

Myofibroblasts and subepithelial fibrosis in bronchial asthma

1 reference

12 December 2020

Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression

1 reference

12 December 2020

Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma

1 reference

12 December 2020

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1 reference

12 December 2020

Bronchial smooth muscle mechanics of a canine model of allergic airway hyperresponsiveness

1 reference

12 December 2020

Responsiveness of bronchial smooth muscle from asthmatic patients to relaxant and contractile agonists

1 reference

12 December 2020

Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine

1 reference

12 December 2020

Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245

1 reference

12 December 2020

The structure of large and small airways in nonfatal and fatal asthma

1 reference

12 December 2020

PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells

1 reference

12 December 2020

The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases

1 reference

12 December 2020

Airway muscle stereology: implications for increased shortening in asthma

1 reference

12 December 2020

Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation

1 reference

12 December 2020

TGF-beta 1 modulates human airway smooth-muscle cell proliferation induced by mitogens

1 reference

12 December 2020

MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes

1 reference

12 December 2020

Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation

1 reference

12 December 2020

Myofibroblast involvement in the allergen-induced late response in mild atopic asthma

1 reference

12 December 2020

Airway responsiveness in two inbred strains of mouse disparate in IgE and IL-4 production

1 reference

12 December 2020

Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis

1 reference

12 December 2020

Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma

1 reference

12 December 2020

TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells

1 reference

12 December 2020

Repeated allergen inhalations induce DNA synthesis in airway smooth muscle and epithelial cells in vivo

1 reference

12 December 2020

Platelet-Derived Growth Factor-BB and Thrombin Activate Phosphoinositide 3-Kinase and Protein Kinase B: Role in Mediating Airway Smooth Muscle Proliferation

1 reference

12 December 2020

Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation

1 reference

12 December 2020

EGF activates ErbB-2 and stimulates phosphatidylinositol 3-kinase in human airway smooth muscle cells

1 reference

12 December 2020

Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle

1 reference

12 December 2020

beta-hexosaminidase-induced activation of p44/42 mitogen-activated protein kinase is dependent on p21Ras and protein kinase C and mediates bovine airway smooth-muscle proliferation

1 reference

12 December 2020

Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle

1 reference

12 December 2020

Bronchoalveolar lavage fluid from asthmatic subjects is mitogenic for human airway smooth muscle

1 reference

12 December 2020

Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes

1 reference

12 December 2020

Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells

1 reference

12 December 2020

Contribution of upregulated airway endothelin-1 expression to airway smooth muscle and epithelial cell DNA synthesis after repeated allergen exposure of sensitized Brown-Norway rats

1 reference

12 December 2020

10.1513/PATS.200705-063VS

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

1 reference

PMCID

2645305