IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury (Q37076743)

18 August 2017

IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury (English)

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18 August 2017

4

Mark H Tuszynski

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18 August 2017

Edmund R Hollis

1

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18 August 2017

Paul Lu

series ordinal

2

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18 August 2017

Armin Blesch

series ordinal

3

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18 August 2017

language of work or name

English

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publication date

2 October 2008

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18 August 2017

Experimental Neurology

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18 August 2017

215

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18 August 2017

1

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18 August 2017

53-59

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describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2632606/fullTextXML

inferred from PubMed Central ID database lookup

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Delayed application of IGF-I and GDNF can rescue already injured postnatal motor neurons

29 September 2017

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Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.

29 September 2017

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Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury

29 September 2017

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Neurite growth promotion by nerve growth factor and insulin-like growth factor-1 in cultured adult sensory neurons: role of phosphoinositide 3-kinase and mitogen activated protein kinase.

29 September 2017

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Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons

29 September 2017

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Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor kappaB.

29 September 2017

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Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

27 June 2018

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Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord

27 June 2018

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Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones.

27 June 2018

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Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord

27 June 2018

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Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

27 June 2018

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27 June 2018

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27 June 2018

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IGF-I specifically enhances axon outgrowth of corticospinal motor neurons.

27 June 2018

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4 September 2018

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BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury

4 September 2018

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IGF-I prevents glutamate-induced motor neuron programmed cell death.

4 September 2018

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In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system

4 September 2018

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The synergistic effects of NGF and IGF-1 on neurite growth in adult sensory neurons: convergence on the PI 3-kinase signaling pathway.

4 September 2018

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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

4 September 2018

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Brain-derived neurotrophic factor applied to the motor cortex promotes sprouting of corticospinal fibers but not regeneration into a peripheral nerve transplant

4 September 2018

1 reference

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Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons.

4 September 2018

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Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse.

4 September 2018

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Adeno-associated viral-mediated insulin-like growth factor delivery protects motor neurons in vitro

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18938163

12 December 2020

inferred from PubMed ID database lookup

Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18938163

12 December 2020

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BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18938163

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.EXPNEUROL.2008.09.014

1 reference

18 August 2017

1 reference

18 August 2017

1 reference