Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop. (Q37077594)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18951974%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop (English)

1 reference

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25 December 2019

1 reference

5

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25 December 2019

author name string

Nicole E Willmarth

1

1 reference

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25 December 2019

Andrea Baillo

2

1 reference

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25 December 2019

Michele L Dziubinski

3

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25 December 2019

Kristy Wilson

4

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25 December 2019

Stephen P Ethier

6

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25 December 2019

publication date

14 October 2008

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25 December 2019

number of pages

8

1 reference

inferred from page(s)

published in

Cellular Signalling

1 reference

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25 December 2019

volume

21

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25 December 2019

issue

2

1 reference

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25 December 2019

page(s)

212-219

1 reference

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Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells

25 December 2019

cites work

1 reference

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The complexity of targeting EGFR signalling in cancer: from expression to turnover

29 September 2017

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The Cbl family proteins: ring leaders in regulation of cell signaling

29 September 2017

1 reference

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Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

29 September 2017

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The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events

29 September 2017

1 reference

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Epidermal growth factor receptor (EGFR) signaling in cancer

29 September 2017

1 reference

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Clathrin-independent endocytosis of ubiquitinated cargos

29 September 2017

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Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

29 September 2017

1 reference

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Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

29 September 2017

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The role of phosphatidylinositol 3'-kinase and its downstream signals in erbB-2-mediated transformation

29 September 2017

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Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis

29 September 2017

1 reference

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Receptor downregulation and multivesicular-body sorting

29 September 2017

1 reference

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A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

29 September 2017

1 reference

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A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin

29 September 2017

1 reference

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Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

29 September 2017

1 reference

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Epidermal growth factor receptor efficiently activates mitogen-activated protein kinase in HeLa cells and Hep2 cells conditionally defective in clathrin-dependent endocytosis

29 September 2017

1 reference

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EGF receptor residues leu(679), leu(680) mediate selective sorting of ligand-receptor complexes in early endosomal compartments

29 September 2017

1 reference

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632975

Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632975

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

29 September 2017

1 reference

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Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma.

29 September 2017

1 reference

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Epiregulin. A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes

29 September 2017

1 reference

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A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

29 September 2017

1 reference

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Autophosphorylation sites on the epidermal growth factor receptor.

29 September 2017

1 reference

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Human transforming growth factor-alpha: precursor structure and expression in E. coli

29 September 2017

1 reference

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Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7

29 September 2017

1 reference

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A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

29 September 2017

1 reference

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Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

29 September 2017

1 reference

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Prognostic markers in triple-negative breast cancer

29 September 2017

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Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination

27 June 2018

1 reference

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Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes: implications for phospholipase C and PI 3-kinase signaling.

27 June 2018

1 reference

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Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.

27 June 2018

1 reference

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Targeted expression of a dominant negative epidermal growth factor receptor in the mammary gland of transgenic mice inhibits pubertal mammary duct development.

27 June 2018

1 reference

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Control of EGF receptor signaling by clathrin-mediated endocytosis.

27 June 2018

1 reference

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Betacellulin: a mitogen from pancreatic beta cell tumors

27 June 2018

1 reference

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Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

27 June 2018

1 reference

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Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor.

4 September 2018

1 reference

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Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

4 September 2018

1 reference

12 December 2020

Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal

1 reference

12 December 2020

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor

1 reference

12 December 2020

Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation

1 reference

12 December 2020

Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction

1 reference

12 December 2020

Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions

1 reference

12 December 2020

Amphiregulin, epidermal growth factor receptor, and estrogen receptor expression in human primary breast cancer

1 reference

12 December 2020

Immunocytochemical localization of Shc and activated EGF receptor in early endosomes after EGF stimulation of HeLa cells

1 reference

12 December 2020

10.1016/J.CELLSIG.2008.10.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18951974%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18951974%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference