Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance (Q37081922)

18 August 2017

Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance (English)

1 reference

18 August 2017

Shilpa Sampathi

1

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18 August 2017

Amruta Bhusari

series ordinal

2

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18 August 2017

Binghui Shen

series ordinal

3

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18 August 2017

Weihang Chai

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4

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18 August 2017

language of work or name

English

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publication date

9 December 2008

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Journal of Biological Chemistry

18 August 2017

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18 August 2017

284

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18 August 2017

6

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18 August 2017

3682-3690

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describes a project that uses

18 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2635043/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Flap endonuclease 1 contributes to telomere stability

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DNA damage response at functional and dysfunctional telomeres

29 September 2017

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Telomere length, stem cells and aging

29 September 2017

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Telomere and telomerase in stem cells

29 September 2017

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Telomerase therapeutics for cancer: challenges and new directions

29 September 2017

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Telomere length homeostasis

29 September 2017

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Telomerase regulation and stem cell behaviour

29 September 2017

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Human telomeres have different overhang sizes at leading versus lagging strands

29 September 2017

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Human telomeres maintain their overhang length at senescence

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Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks

29 September 2017

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29 September 2017

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Flap endonuclease 1: a central component of DNA metabolism

29 September 2017

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29 September 2017

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Stimulation of flap endonuclease-1 by the Bloom's syndrome protein

29 September 2017

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29 September 2017

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CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation

29 September 2017

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Replication proteins influence the maintenance of telomere length and telomerase protein stability

29 September 2017

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Differential processing of leading- and lagging-strand ends at Saccharomyces cerevisiae telomeres revealed by the absence of Rad27p nuclease

29 September 2017

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Human Ku70/80 associates physically with telomerase through interaction with hTERT

29 September 2017

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Interactions between telomerase and primase physically link the telomere and chromosome replication machinery

29 September 2017

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Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

29 September 2017

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Senescence Induced by Altered Telomere State, Not Telomere Loss

29 September 2017

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Cellular senescence, cancer and aging: the telomere connection

29 September 2017

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In vitro reconstitution of the end replication problem

29 September 2017

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Telomeres and telomerase: implications for cancer and aging

29 September 2017

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The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

29 September 2017

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The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis

29 September 2017

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Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.

29 September 2017

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Coordinate regulation of G- and C strand length during new telomere synthesis

29 September 2017

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Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase

29 September 2017

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Telomerase activity in human cancer.

29 September 2017

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Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae

29 September 2017

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The characterization of a mammalian DNA structure-specific endonuclease

29 September 2017

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Telomerase and DNA end replication: no longer a lagging strand problem?

29 September 2017

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A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

29 September 2017

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

29 September 2017

1 reference

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Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

29 September 2017

1 reference

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Recognition and elongation of telomeres by telomerase

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635043

29 September 2017

https://api.crossref.org/works/10.1074%2FJBC.M805362200

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635043

The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635043

Fen1 mutations result in autoimmunity, chronic inflammation and cancers

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635043

Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635043

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

3 September 2018

1 reference

12 December 2020

Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomerase

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12 December 2020

CDC17: an essential gene that prevents telomere elongation in yeast

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12 December 2020

Telomere-end processing the terminal nucleotides of human chromosomes

1 reference

12 December 2020

Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta

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12 December 2020

The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres

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12 December 2020

Identifiers

DOI

10.1074/JBC.M805362200

1 reference

18 August 2017

1 reference

18 August 2017

1 reference