Exploring the origins of binding specificity through the computational redesign of calmodulin (Q37088361)

18 August 2017

Exploring the origins of binding specificity through the computational redesign of calmodulin (English)

1 reference

18 August 2017

Julia M Shifman

1

1 reference

PMCID

263780

18 August 2017

Stephen L Mayo

series ordinal

2

1 reference

PMCID

263780

18 August 2017

language of work or name

English

0 references

publication date

3 November 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

100

1 reference

18 August 2017

23

1 reference

18 August 2017

13274-13279

1 reference

The dead-end elimination theorem and its use in protein side-chain positioning

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Optimization by Simulated Annealing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Exact rotamer optimization for protein design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Enzyme-like proteins by computational design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca(2+)/calmodulin-dependent kinase kinase peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Optimization of binding electrostatics: charge complementarity in the barnase-barstar protein complex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Computational design of an integrin I domain stabilized in the open high affinity conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Calmodulin: a prototypical calcium sensor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Trading accuracy for speed: A quantitative comparison of search algorithms in protein sequence design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Energy functions for protein design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Electrostatic interactions in the GCN4 leucine zipper: substantial contributions arise from intramolecular interactions enhanced on binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Computational protein design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Design, structure and stability of a hyperthermophilic protein variant

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

De novo protein design: fully automated sequence selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

MOLMOL: a program for display and analysis of macromolecular structures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Backbone-dependent rotamer library for proteins. Application to side-chain prediction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Ca(2+)-binding and structural dynamics in the functions of calmodulin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Molecular and structural basis of target recognition by calmodulin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

How calmodulin binds its targets: sequence independent recognition of amphiphilic alpha-helices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Protein binding versus protein folding: the role of hydrophilic bridges in protein associations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

Recursive PCR: a novel technique for total gene synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263780

CALMODULIN AND CALMODULIN-BINDING PROTEINS IN PLANTS.

27 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Energetics of target peptide binding by calmodulin reveals different modes of binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Spectroscopic characterization of the interaction between calmodulin-dependent protein kinase I and calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Achieving stability and conformational specificity in designed proteins via binary patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Modulating calmodulin binding specificity through computational protein design

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Role of water mediated interactions in protein-protein recognition landscapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Designing protein beta-sheet surfaces by Z-score optimization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Automated design of specificity in molecular recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Energetics of target peptide recognition by calmodulin: a calorimetric study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Recognition and characterization of calmodulin-binding sequences in peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

Fluorescence properties of calmodulin-binding peptides reflect alpha-helical periodicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2234277100

21 January 2018

Identifiers

DOI

10.1073/PNAS.2234277100

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference

PMCID

263780