Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen (Q37101433)

18 August 2017

Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen (English)

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18 August 2017

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Gauri Sabnis

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author name string

Adam Schayowitz

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18 August 2017

Olga Goloubeva

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18 August 2017

Luciana Macedo

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18 August 2017

Angela Brodie

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18 August 2017

language of work or name

English

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publication date

3 February 2009

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18 August 2017

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18 August 2017

69

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18 August 2017

1416-1428

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18 August 2017

4

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describes a project that uses

18 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2644349/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Role of receptor complexes in the extranuclear actions of estrogen receptor alpha in breast cancer

14 September 2017

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Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer.

14 September 2017

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Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer

14 September 2017

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EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization.

14 September 2017

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Clinical trials of intracellular signal transductions inhibitors for breast cancer--a strategy to overcome endocrine resistance

14 September 2017

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Combinations of endocrine and biological agents: present status of therapeutic and presurgical investigations

14 September 2017

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Therapeutic observations in MCF-7 aromatase xenografts.

14 September 2017

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Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer

14 September 2017

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Adaptive hypersensitivity following long-term estrogen deprivation: involvement of multiple signal pathways

14 September 2017

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Resistance to trastuzumab: a necessary evil or a temporary challenge?

14 September 2017

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Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer.

14 September 2017

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The role of mitogen-activated protein (MAP) kinase in breast cancer

14 September 2017

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The predictive value of HER2 in breast cancer

14 September 2017

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Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo

14 September 2017

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

14 September 2017

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Xenograft models for aromatase inhibitor studies

14 September 2017

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Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens

29 September 2017

1 reference

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Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors

29 September 2017

1 reference

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ErbB receptor signaling and therapeutic resistance to aromatase inhibitors

29 September 2017

1 reference

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Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts

29 September 2017

1 reference

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A novel role of sodium butyrate in the regulation of cancer-associated aromatase promoters I.3 and II by disrupting a transcriptional complex in breast adipose fibroblasts

29 September 2017

1 reference

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Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole

29 September 2017

1 reference

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The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation

29 September 2017

1 reference

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Chromatin immunoprecipitation analysis of gene expression in the rat uterus in vivo: estrogen-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

Up-regulation of pS2 expression during the development of adenocarcinomas but not squamous cell carcinomas of the uterine cervix, independently of expression of c-jun or oestrogen and progesterone receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction

29 September 2017

1 reference

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Nuclear localization of p185neu tyrosine kinase and its association with transcriptional transactivation

29 September 2017

1 reference

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Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells

29 September 2017

1 reference

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Characterization of a novel tripartite nuclear localization sequence in the EGFR family.

27 June 2018

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Model systems: mechanisms involved in the loss of sensitivity to letrozole

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644349

The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity

3 September 2018

1 reference

12 December 2020

A new nude mouse model for postmenopausal breast cancer using MCF-7 cells transfected with the human aromatase gene

1 reference

12 December 2020

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival

1 reference

12 December 2020

MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors

1 reference

12 December 2020

The effect of estrogen on aromatase and vascular endothelial growth factor messenger ribonucleic acid in the normal nonhuman primate mammary gland

1 reference

12 December 2020

A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the Human Genome Project

1 reference

12 December 2020

10.1158/0008-5472.CAN-08-0857

Identifiers

DOI

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18 August 2017

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18 August 2017

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