Rational vector design for efficient non-viral gene delivery: challenges facing the use of plasmid DNA. (Q37104735)

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3 January 2020

review article

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title

Rational vector design for efficient non-viral gene delivery: challenges facing the use of plasmid DNA (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18327557%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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1

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3 January 2020

Reingard Grabherr

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18327557%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Juergen Mairhofer

series ordinal

1

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18 August 2017

publication date

1 June 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18327557%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

published in

Molecular Biotechnology

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3 January 2020

volume

39

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3 January 2020

issue

2

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3 January 2020

page(s)

97-104

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https://scigraph.springernature.com/pub.10.1007/s12033-008-9046-7

3 January 2020

exact match

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cites work

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A new DNA vehicle for nonviral gene delivery: supercoiled minicircle

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Molecular structure of a left-handed double helical DNA fragment at atomic resolution

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Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency

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E. coli growth inhibition by a high copy number derivative of plasmid pBR322

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Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression.

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A Toll-like receptor recognizes bacterial DNA

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pCOR: a new design of plasmid vectors for nonviral gene therapy

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Effect of DNA topology on the transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes

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MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli

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A novel antibiotic free plasmid selection system: advances in safe and efficient DNA therapy.

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DNA H form requires a homopurine-homopyrimidine mirror repeat.

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Timing, self-control and a sense of direction are the secrets of multicopy plasmid stability

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The extended and eccentric E-DNA structure induced by cytosine methylation or bromination

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Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs

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CpG DNA and LPS induce distinct patterns of activation in human monocytes

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Plasmid DNA vaccines: investigation of integration into host cellular DNA following intramuscular injection in mice

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The molecular configuration of deoxyribonucleic acid III. X-ray diffraction study of the C form of the lithium salt

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Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells

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Intracellular routing of plasmid DNA during non-viral gene transfer.

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The role of polyadenylation signal secondary structures on the resistance of plasmid vectors to nucleases.

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Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

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Using ColE1-derived RNA I for suppression of a bacterially encoded gene: implication for a novel plasmid addiction system.

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Stretched and overwound DNA forms a Pauling-like structure with exposed bases

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Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells

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Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors.

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Structural details of double-helix observed for DNAs containing alternating purine and pyrimidine sequences

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Application of L-DNA as a molecular tag.

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Nonviral DNA vectors for immunization and therapy: design and methods for their obtention

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Inflammatory responses following direct injection of plasmid DNA into skeletal muscle

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12 December 2020

Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence

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12 December 2020

Expression of the neomycin-resistance (neo) gene induces alterations in gene expression and metabolism.

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12 December 2020

Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer

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12 December 2020

Nucleotide sequence determination of bacteriophage T2 and T6 species I ribonucleic acids

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12 December 2020

Size-dependent DNA mobility in cytoplasm and nucleus

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12 December 2020

Contribution of Plasmid DNA to Inflammation in the Lung after Administration of Cationic Lipid:pDNA Complexes

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12 December 2020

pBR322 contains glucocorticoid regulatory element DNA consensus sequences

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12 December 2020

Eukaryotic regulatory elements lurking in plasmid DNA: the activator protein-1 site in pUC.

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12 December 2020

Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines.

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12 December 2020

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12 December 2020

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12 December 2020

Commonly used cat reporter vectors contain a cAMP-inducible, cryptic enhancer that co-operates with NF-kappa B-sites.

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12 December 2020

DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor

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12 December 2020

Stability of pBR322-derived plasmids

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12 December 2020

Investigations of the effect of DNA size in transient transfection assay using dual luciferase system

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12 December 2020

The effects of plasmid copy number and sequence context upon transfection efficiency

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12 December 2020

Progress and problems with the use of viral vectors for gene therapy

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12 December 2020