The role of NHE-1 in myocardial hypertrophy and remodelling (Q37105423)

18 August 2017

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title

The role of NHE-1 in myocardial hypertrophy and remodelling (English)

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18 August 2017

Morris Karmazyn

1

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PubMed ID

18329039

18 August 2017

Ana Kilić

series ordinal

2

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PubMed ID

18329039

18 August 2017

Sabzali Javadov

series ordinal

3

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18 August 2017

9 February 2008

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Journal of Molecular and Cellular Cardiology

18 August 2017

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18 August 2017

44

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18 August 2017

4

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18 August 2017

647-653

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Sodium-hydrogen exchanger, cardiac overload, and myocardial hypertrophy

18 August 2017

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Phorbol ester activation of the rat vascular myocyte Na(+)-H(+) exchanger isoform 1

7 January 2021

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Phosphorylation and regulation of the Na+/H+ exchanger through mitogen-activated protein kinase

7 January 2021

1 reference

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Protein kinase-mediated regulation of the Na(+)/H(+) exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways

7 January 2021

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Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium

7 January 2021

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Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Role of Na(+)-H+ exchange in mediating effects of endothelin-1 on normal and ischemic/reperfused hearts.

7 January 2021

1 reference

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The modulatory effects of endothelin-1, carbachol and isoprenaline upon Na(+)-H+ exchange in dog cardiac Purkinje fibres

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Endothelin and angiotensin II stimulation of Na+-H+ exchange is impaired in cardiac hypertrophy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Alpha 1-adrenergic stimulation of Na-H exchange in cardiac myocytes

7 January 2021

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Alpha1-adrenergic stimulation of sarcolemmal Na+-H+ exchanger activity in rat ventricular myocytes: evidence for selective mediation by the alpha1A-adrenoceptor subtype.

7 January 2021

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The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing"

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy

7 January 2021

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Stretch-induced alkalinization of feline papillary muscle: an autocrine-paracrine system

7 January 2021

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The role of Na+/H+ exchange in norepinephrine-induced protein synthesis in neonatal cultured rat cardiomyocytes

7 January 2021

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Angiotensin and endothelin: messengers that couple ventricular stretch to the Na+/H+ exchanger and cardiac hypertrophy

7 January 2021

1 reference

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Na+/H+ exchange hyperactivity and myocardial hypertrophy: are they linked phenomena?

7 January 2021

1 reference

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Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Sarcolemmal Na+/H+ exchanger activity and expression in human ventricular myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Influence of pHi and creatine phosphate on alpha-adrenoceptor-mediated cardiac hypertrophy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Regression of isoproterenol-induced cardiac hypertrophy by Na+/H+ exchanger inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Role of endothelin-1, sodium hydrogen exchanger-1 and mitogen activated protein kinase (MAPK) activation in glucose-induced cardiomyocyte hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Aldosterone Increases NHE-1 Expression and Induces NHE-1-Dependent Hypertrophy in Neonatal Rat Ventricular Myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Mineralocorticoid action and sodium-hydrogen exchange: studies in experimental cardiac fibrosis

7 January 2021

1 reference

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Effects of Na(+)-H+ exchange blocker amiloride on left ventricular remodeling after anterior myocardial infarction in rats

7 January 2021

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Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Regression of hypertensive myocardial fibrosis by Na(+)/H(+) exchange inhibition

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Phosphodiesterase 5A inhibition induces Na+/H+ exchanger blockade and protection against myocardial infarction.

7 January 2021

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Altered Na(+)- H(+)- exchange activity in the spontaneously hypertensive perfused rat heart

7 January 2021

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pHi regulation in myocardium of the spontaneously hypertensive rat. Compensated enhanced activity of the Na(+)-H+ exchanger

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Enalapril induces regression of cardiac hypertrophy and normalization of pHi regulatory mechanisms

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice

7 January 2021

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NHE-1-dependent intracellular sodium overload in hypertrophic hereditary cardiomyopathy: prevention by NHE-1 inhibitor.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Enhanced activity of the myocardial Na+/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice.

7 January 2021

1 reference

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Local actions of atrial natriuretic peptide counteract angiotensin II stimulated cardiac remodeling.

7 January 2021

1 reference

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Atrial Natriuretic Peptide Has Different Effects on Contractility and Intracellular pH in Normal and Hypertrophied Myocytes From Pressure-Overloaded Hearts

7 January 2021

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Enhanced activity of the myocardial Na+/H+ exchanger contributes to left ventricular hypertrophy in the Goto-Kakizaki rat model of type 2 diabetes: critical role of Akt

7 January 2021

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Contribution of NHE-1 to cell length shortening of normal and failing rabbit cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Na(+)influx via Na(+)/H(+)exchange activates protein kinase C isozymes delta and epsilon in cultured neonatal rat cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Normalization of the calcineurin pathway underlies the regression of hypertensive hypertrophy induced by Na+/H+ exchanger-1 (NHE-1) inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Endothelin-1 induced hypertrophic effect in neonatal rat cardiomyocytes: Involvement of Na+/H+ and Na+/Ca2+ exchangers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

7 January 2021

1 reference

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Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection

7 January 2021

1 reference

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NHE-1 inhibition improves impaired mitochondrial permeability transition and respiratory function during postinfarction remodelling in the rat.

7 January 2021

1 reference

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The mitochondrial permeability transition pore and its role in cell death

7 January 2021

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Role of the mitochondrial permeability transition in myocardial disease

7 January 2021

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Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

7 January 2021

1 reference

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NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Antihypertrophic effect of Na+/H+ exchanger isoform 1 inhibition is mediated by reduced mitogen-activated protein kinase activation secondary to improved mitochondrial integrity and decreased generation of mitochondrial-derived reactive oxygen speci

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.01.005

The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

7 January 2021

1 reference

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10.1016/J.YJMCC.2008.01.005

7 January 2021

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18329039