GNRH induces the unfolded protein response in the LbetaT2 pituitary gonadotrope cell line (Q37106828)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18974261%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

GNRH induces the unfolded protein response in the LbetaT2 pituitary gonadotrope cell line (English)

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25 December 2019

0 references

1

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25 December 2019

author name string

Sharon J Santos

series ordinal

2

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25 December 2019

Mark A Lawson

series ordinal

3

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25 December 2019

publication date

30 October 2008

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25 December 2019

published in

Molecular Endocrinology

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25 December 2019

volume

23

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25 December 2019

issue

1

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25 December 2019

page(s)

100-112

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Unconventional splicing of XBP-1 mRNA in the unfolded protein response

25 December 2019

cites work

1 reference

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Signal integration in the endoplasmic reticulum unfolded protein response

14 September 2017

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Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2.

14 September 2017

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Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

14 September 2017

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Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

14 September 2017

1 reference

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Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress

14 September 2017

1 reference

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Activin modulates the transcriptional response of LbetaT2 cells to gonadotropin-releasing hormone and alters cellular proliferation

14 September 2017

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Divergent roles of IRE1alpha and PERK in the unfolded protein response

14 September 2017

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From acute ER stress to physiological roles of the Unfolded Protein Response

14 September 2017

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14 September 2017

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The pituitary effects of GnRH.

14 September 2017

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The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

14 September 2017

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Regulation of gonadotropin subunit gene transcription

14 September 2017

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Molecular mechanisms of translational control

14 September 2017

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Multiple and overlapping combinatorial codes orchestrate hormonal responsiveness and dictate cell-specific expression of the genes encoding luteinizing hormone

14 September 2017

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Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response

14 September 2017

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Regulation of mRNA translation by protein folding in the endoplasmic reticulum

14 September 2017

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Oxidative protein folding in eukaryotes: mechanisms and consequences

14 September 2017

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Acute regulation of translation initiation by gonadotropin-releasing hormone in the gonadotrope cell line LbetaT2

14 September 2017

1 reference

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Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

14 September 2017

1 reference

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A trip to the ER: coping with stress

14 September 2017

1 reference

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Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

14 September 2017

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Starting the protein synthesis machine: eukaryotic translation initiation.

14 September 2017

1 reference

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

14 September 2017

1 reference

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Gonadotropin-releasing hormone receptor-mediated growth suppression of immortalized LbetaT2 gonadotrope and stable HEK293 cell lines

14 September 2017

1 reference

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Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptability

14 September 2017

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14 September 2017

All roads lead to ATF4

1 reference

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

14 September 2017

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Proestrous surge of gonadotropin-releasing hormone secretion inhibits apoptosis of anterior pituitary cells in cycling female rats

14 September 2017

1 reference

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GnRH pulse frequency modulation of gonadotropin subunit gene transcription in normal gonadotropes-assessment by primary transcript assay provides evidence for roles of GnRH and follistatin

14 September 2017

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Coupling of GnRH concentration and the GnRH receptor-activated gene program

14 September 2017

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

14 September 2017

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Gene-specific regulation by general translation factors

14 September 2017

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Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor

14 September 2017

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Gonadotropin-releasing hormone receptor-coupled gene network organization

14 September 2017

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Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry

14 September 2017

1 reference

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Plasma cell differentiation requires the transcription factor XBP-1

14 September 2017

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

14 September 2017

1 reference

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

14 September 2017

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

14 September 2017

1 reference

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Global and specific translational regulation in the genomic response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source

14 September 2017

1 reference

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ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

14 September 2017

1 reference

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Perk is essential for translational regulation and cell survival during the unfolded protein response

14 September 2017

1 reference

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

14 September 2017

1 reference

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An essential role in liver development for transcription factor XBP-1

14 September 2017

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Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

14 September 2017

1 reference

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Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

14 September 2017

1 reference

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gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

14 September 2017

1 reference

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The involvement of phosphatidylinositol 3-kinase in gonadotropin-releasing hormone-induced gonadotropin alpha- and FSHbeta-subunit genes expression in clonal gonadotroph LbetaT2 cells

14 September 2017

1 reference

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The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.

29 September 2017

1 reference

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Protection of Renal Epithelial Cells against Oxidative Injury by Endoplasmic Reticulum Stress Preconditioning Is Mediated by ERK1/2 Activation

29 September 2017

1 reference

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Identification of distinct gene expression profiles associated with treatment of LβT2 cells with gonadotropin-releasing hormone agonist using microarray analysis

29 September 2017

1 reference

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Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines

29 September 2017

1 reference

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Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice

29 September 2017

1 reference

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The L beta T2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion

29 September 2017

1 reference

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Translational regulation of the gonadotropin-releasing hormone receptor in alpha T3-1 cells

29 September 2017

1 reference

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Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways

29 September 2017

1 reference

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Gonadotropin-releasing hormone stimulates glycoprotein hormone alpha-subunit messenger ribonucleic acid (mRNA) levels in alpha T3 cells by increasing transcription and mRNA stability.

27 June 2018

1 reference

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Inhibition of translational initiation in eukaryotic cells by calcium ionophore

27 June 2018

1 reference

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Pulsatile gonadotropin-releasing hormone modifies polyadenylation of gonadotropin subunit messenger ribonucleic acids

27 June 2018

1 reference

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PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

27 June 2018

1 reference

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PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646596

Constitutively active Gq impairs gonadotropin-releasing hormone-induced intracellular signaling and luteinizing hormone secretion in LbetaT2 cells

3 September 2018

1 reference

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Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock

3 September 2018

1 reference

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In vivo gonadotropin-releasing hormone secretion in female rats during peripubertal development and on proestrus.

3 September 2018

1 reference

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Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils

3 September 2018

1 reference

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Activation of translation in pituitary gonadotrope cells by gonadotropin-releasing hormone

3 September 2018

1 reference

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The ER function BiP is a master regulator of ER function

3 September 2018

1 reference

12 December 2020

Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II

1 reference

12 December 2020

The effect of serum, EGF, PGF2 alpha and insulin on S6 phosphorylation and the initiation of protein and DNA synthesis

1 reference

12 December 2020

Dynamics of gonadotropin-releasing hormone release during a pulse

1 reference

12 December 2020

BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+

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12 December 2020

Identifiers

DOI

10.1210/ME.2008-0071

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18974261%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18974261%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

18974261

1 reference