Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis. (Q37114231)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255448%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis (English)

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22 January 2020

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4

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22 January 2020

author name string

Danielle Burger

1

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22 January 2020

Nicolas Molnarfi

2

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22 January 2020

Martin S Weber

3

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22 January 2020

Mahdia Benkhoucha

5

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22 January 2020

Lyssia Gruaz

6

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22 January 2020

Michel Chofflon

7

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22 January 2020

Scott S Zamvil

8

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22 January 2020

Patrice H Lalive

9

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22 January 2020

language of work or name

English

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publication date

2 March 2009

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Proceedings of the National Academy of Sciences of the United States of America

22 January 2020

published in

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22 January 2020

volume

106

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22 January 2020

page(s)

4355-4359

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22 January 2020

issue

11

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The identification of a small molecule inhibitor that specifically reduces T cell-mediated adaptive but not LPS-mediated innate immunity by T cell membrane-monocyte contact bioassay

22 January 2020

cites work

1 reference

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Mechanism of action of glatiramer acetate in treatment of multiple sclerosis

14 September 2017

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Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications

14 September 2017

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Role of Very-late Antigen-4 (VLA-4) in Myelin Basic Protein-primed T Cell Contact-induced Expression of Proinflammatory Cytokines in Microglial Cells

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14 September 2017

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Cell contact-mediated signaling of monocytes by stimulated T cells: a major pathway for cytokine induction.

14 September 2017

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Lymphocyte activation gene-3, a MHC class II ligand expressed on activated T cells, stimulates TNF-alpha and IL-12 production by monocytes and dendritic cells.

14 September 2017

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Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

14 September 2017

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Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells

14 September 2017

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Opposite effects of IFN beta on cytokine homeostasis in LPS- and T cell contact-activated human monocytes

14 September 2017

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Glatiramer acetate blocks the activation of THP-1 cells by interferon-gamma

14 September 2017

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Glatiramer acetate treatment does not modify the clinical course of (NZB x BXSB)F1 lupus murine model

29 September 2017

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Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

3 September 2018

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HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.

3 September 2018

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Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis

3 September 2018

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Differential induction of IL-1beta and TNF by CD40 ligand or cellular contact with stimulated T cells depends on the maturation stage of human monocytes

3 September 2018

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Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

3 September 2018

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Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo

3 September 2018

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Induction of IL-10 in rat peritoneal macrophages and dendritic cells by glatiramer acetate

3 September 2018

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Glatiramer Acetate (Copolymer-1, Copaxone) Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells

3 September 2018

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Cytokine production in T lymphocyte-microglia interaction is attenuated by glatiramer acetate: a mechanism for therapeutic efficacy in multiple sclerosis

3 September 2018

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Glatiramer acetate and IFN-beta act on dendritic cells in multiple sclerosis

3 September 2018

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Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes

3 September 2018

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Mechanisms of action of glatiramer acetate in multiple sclerosis

3 September 2018

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3 September 2018

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Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity

3 September 2018

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12 December 2020

Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier

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12 December 2020

The adhesion molecule and cytokine profile of multiple sclerosis lesions

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12 December 2020

Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats

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12 December 2020

Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to IFN-beta treatment

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12 December 2020

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

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12 December 2020

Inhibition of naive Th1 CD4+ T cells by glatiramer acetate in multiple sclerosis

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12 December 2020

The therapeutic effect of glatiramer acetate in a murine model of inflammatory bowel disease is mediated by anti-inflammatory T-cells

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12 December 2020

Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity

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12 December 2020

Copolymer 1 inhibits experimental autoimmune uveoretinitis

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12 December 2020

Glatiramer acetate in the treatment of multiple sclerosis

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12 December 2020

Exacerbation of autoimmune arthritis by copolymer-I through promoting type 1 immune response and autoantibody production

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12 December 2020

Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0812183106

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22 January 2020

0 references

1 reference

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22 January 2020

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