Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial. (Q37117056)

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scientific article published on 16 April 2012

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English	Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial.	scientific article published on 16 April 2012

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scholarly article

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29 January 2020

Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial (English)

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29 January 2020

0 references

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LDL cholesterol

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1 reference

based on heuristic

inferred from title

mipomersen parent acid

1 reference

based on heuristic

inferred from title

8

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29 January 2020

John J. P. Kastelein

11

object named as

John J P Kastelein

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29 January 2020

7

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Aart J Nederveen

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29 January 2020

author name string

Maartje E Visser

1

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29 January 2020

Gilbert Wagener

2

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29 January 2020

Brenda F Baker

3

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29 January 2020

Richard S Geary

4

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29 January 2020

Joanne M Donovan

5

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29 January 2020

Ulrich H W Beuers

6

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29 January 2020

Mieke D Trip

9

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29 January 2020

Dick C G Basart

10

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29 January 2020

Erik S G Stroes

12

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publication date

16 April 2012

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29 January 2020

European Heart Journal

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29 January 2020

33

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29 January 2020

9

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29 January 2020

1142-1149

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29 January 2020

Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery dis

1 reference

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Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice.

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Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial

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The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysis

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Apolipoprotein B synthesis inhibition: results from clinical trials

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14 September 2017

Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia

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14 September 2017

Efficacy of statins in familial hypercholesterolaemia: a long term cohort study

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The broad spectrum of statin myopathy: from myalgia to rhabdomyolysis

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14 September 2017

Molecular diagnosis of hypobetalipoproteinemia: an ENID review

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Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

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Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy.

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Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force.

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Pathophysiology of nonalcoholic steatohepatitis

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Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial

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14 September 2017

Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients--the PRIMO study

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14 September 2017

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

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14 September 2017

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population

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14 September 2017

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

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14 September 2017

Risk of fatal coronary heart disease in familial hypercholesterolaemia. Scientific Steering Committee on behalf of the Simon Broome Register Group

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14 September 2017

Hepatic steatosis does not cause insulin resistance in people with familial hypobetalipoproteinaemia

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27 June 2018

Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis

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27 June 2018

Hepatic steatosis and insulin resistance: does etiology make a difference?

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27 June 2018

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis

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27 June 2018

Risks of ischaemic heart-disease in familial hyperlipoproteinaemic states

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27 June 2018

The tolerability and efficacy of low-dose simvastatin in statin-intolerant patients.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3751967

3 September 2018

Effect of mipomersen, an apolipoprotein B synthesis inhibitor, on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3751967

3 September 2018

Efficacy and safety of mipomersen, an antisense inhibitor of apolipoprotein B, in hypercholesterolemic subjects receiving stable statin therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3751967

3 September 2018

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

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Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

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Reproducibility of 3.0 Tesla magnetic resonance spectroscopy for measuring hepatic fat content

1 reference

https://pubmed.ncbi.nlm.nih.gov/22507979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22507979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EURHEARTJ/EHS023

1 reference

Europe PubMed Central

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29 January 2020

1 reference

Europe PubMed Central

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29 January 2020

1 reference

Europe PubMed Central

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29 January 2020

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