Why is HDL functionally deficient in type 2 diabetes? (Q37119301)

18 August 2017

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title

Why is HDL functionally deficient in type 2 diabetes? (English)

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18 August 2017

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Anatol Kontush

1

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PubMed ID

18366999

18 August 2017

M John Chapman

series ordinal

2

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18 August 2017

1 February 2008

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18 August 2017

Current diabetes report

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18 August 2017

8

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18 August 2017

1

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18 August 2017

51-59

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https://scigraph.springernature.com/pub.10.1007/s11892-008-0010-5

18 August 2017

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Oxidative inactivation of paraoxonase--implications in diabetes mellitus and atherosclerosis

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21 January 2018

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Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may Be due to the abnormal composition of HDL.

21 January 2018

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Oxidized low-density lipoprotein-induced apoptosis

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The relationship of chemical modification of membrane proteins and plasma lipoproteins to reduced membrane fluidity of erythrocytes from diabetic subjects

21 January 2018

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12 December 2020

Characterization of the non enzymatic glycation of high density lipoprotein in diabetic patients

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12 December 2020

Effects of the neutral lipid content of high density lipoprotein on apolipoprotein A-I structure and particle stability

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12 December 2020

Inability of HDL from abdominally obese subjects to counteract the inhibitory effect of oxidized LDL on vasorelaxation

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12 December 2020

The role of high-density lipoproteins in oxidation and inflammation

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The failure of torcetrapib: was it the molecule or the mechanism?

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Metabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activity

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12 December 2020

Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes

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12 December 2020

Susceptibility of low- and high-density lipoproteins from diabetic subjects to in vitro oxidative modification

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HDL oxidability and its protective effect against LDL oxidation in Type 2 diabetic patients.

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Serum amyloid A: the "other" inflammatory protein

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Pharmacological modulation of cholesteryl ester transfer protein, a new therapeutic target in atherogenic dyslipidemia

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12 December 2020

High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI

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12 December 2020

Role of Serum Amyloid A During Metabolism of Acute-Phase HDL by Macrophages

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12 December 2020

Defective antioxidative activity of small dense HDL3 particles in type 2 diabetes: relationship to elevated oxidative stress and hyperglycaemia.

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12 December 2020

Cholesterol efflux from Fu5AH hepatoma cells induced by plasma of subjects with or without coronary artery disease and non-insulin-dependent diabetes: importance of LpA-I:A-II particles and phospholipid transfer protein

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12 December 2020

Myeloperoxidase: an inflammatory enzyme for generating dysfunctional high density lipoprotein.

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12 December 2020

Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.

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12 December 2020

Metabolic syndrome features small, apolipoprotein A-I-poor, triglyceride-rich HDL3 particles with defective anti-apoptotic activity

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12 December 2020

Glycation impairs high-density lipoprotein function

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12 December 2020

Circulating levels of nitrated apolipoprotein A-I are increased in type 2 diabetic patients

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12 December 2020

Nonenzymatic Glycosylation of HDL and Impaired HDL-Receptor–Mediated Cholesterol Efflux

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12 December 2020

Serum paraoxonase is reduced in type 1 diabetic patients compared to non-diabetic, first degree relatives; influence on the ability of HDL to protect LDL from oxidation

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ProteinChip technology: a new and facile method for the identification and measurement of high-density lipoproteins apoA-I and apoA-II and their glycosylated products in patients with diabetes and cardiovascular disease

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12 December 2020

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Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment

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12 December 2020

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Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease

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12 December 2020

Antioxidative activity of HDL particle subspecies is impaired in hyperalphalipoproteinemia: relevance of enzymatic and physicochemical properties.

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12 December 2020

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12 December 2020

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12 December 2020

Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells

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12 December 2020

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12 December 2020

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.

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12 December 2020

Inability of HDL from type 2 diabetic patients to counteract the inhibitory effect of oxidised LDL on endothelium-dependent vasorelaxation

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12 December 2020

Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited

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12 December 2020

Glycation of high-density lipoprotein does not increase its susceptibility to oxidation or diminish its cholesterol efflux capacity

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12 December 2020

Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment

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12 December 2020

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

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12 December 2020

Protective effect of paraoxonase activity in high-density lipoproteins against erythrocyte membranes peroxidation: a comparison between healthy subjects and type 1 diabetic patients

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12 December 2020

Effect of glycation of high density lipoproteins on their physicochemical properties and on paraoxonase activity

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12 December 2020

Comparison of antioxidant activity in lipoprotein fractions from insulin-dependent diabetics and healthy controls.

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12 December 2020

Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis

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12 December 2020

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?

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12 December 2020

Alterations in the main steps of reverse cholesterol transport in male patients with primary hypertriglyceridemia and low HDL-cholesterol levels

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12 December 2020

Persistent abnormalities in lipoprotein composition in noninsulin-dependent diabetes after intensive insulin therapy

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12 December 2020

In vivo glucosylated LpA-I subfraction. Evidence for structural and functional alterations

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12 December 2020

Glycated high-density lipoprotein induces apoptosis of endothelial cells via a mitochondrial dysfunction

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12 December 2020

10.1007/S11892-008-0010-5

Identifiers

DOI

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18 August 2017

1 reference

PubMed ID

18366999