Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. (Q37119764)

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scientific article published on 06 August 2008

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English	Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.	scientific article published on 06 August 2008

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11 January 2020

Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva (English)

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11 January 2020

fibrodysplasia ossificans progressiva

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11 January 2020

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Toru Fukuda

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11 January 2020

Masakazu Kohda

2

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11 January 2020

Kazuhiro Kanomata

3

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Junya Nojima

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Atsushi Nakamura

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Jyunji Kamizono

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Yasuo Noguchi

7

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Kiyofumi Iwakiri

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Takeo Kondo

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Junichi Kurose

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Ken-ichi Endo

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Takeshi Awakura

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Junichi Fukushi

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Yasuharu Nakashima

14

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Tomohiro Chiyonobu

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Akira Kawara

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Yoshihiro Nishida

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11 January 2020

Ikuo Wada

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11 January 2020

Masumi Akita

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11 January 2020

Tetsuo Komori

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Konosuke Nakayama

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Akira Nanba

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Yuichi Maruki

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Tetsuya Yoda

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Hiroshi Tomoda

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Eileen M Shore

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11 January 2020

Frederick S Kaplan

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Kohei Miyazono

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Masaru Matsuoka

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Kenji Ikebuchi

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Akira Ohtake

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Hiromi Oda

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Eijiro Jimi

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Ichiro Owan

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Yasushi Okazaki

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Takenobu Katagiri

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6 August 2008

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Journal of Biological Chemistry

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11 January 2020

7149-7156

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11 January 2020

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

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Bone morphogenetic protein-9 is a circulating vascular quiescence factor

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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

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Dysregulation of the BMP-4 signaling pathway in fibrodysplasia ossificans progressiva

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

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Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction

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Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

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14 September 2017

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses

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GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

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Fibrodysplasia ossificans progressiva: a clue from the fly?

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14 September 2017

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29 September 2017

Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts.

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Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin

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29 September 2017

Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva

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29 September 2017

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27 June 2018

Purification and identification of a BMP-like factor from bovine serum.

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3 September 2018

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3 September 2018

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3 September 2018

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1 reference

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3 September 2018

Fibrodysplasia ossificans progressiva. The clinical features and natural history of 34 patients.

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3 September 2018

The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients

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12 December 2020

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The histopathology of fibrodysplasia ossificans progressiva. An endochondral process

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12 December 2020

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Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva

1 reference

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Inhibitory effects of activin-A on osteoblast differentiation during cultures of fetal rat calvarial cells

1 reference

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12 December 2020

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Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome

1 reference

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12 December 2020

based on heuristic

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Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

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Hematopoietic stem-cell contribution to ectopic skeletogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ACVR1 617G>A mutation is also recurrent in three Japanese patients with fibrodysplasia ossificans progressiva

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

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10.1074/JBC.M801681200

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11 January 2020

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11 January 2020

1 reference

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11 January 2020

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