PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2 (Q37122943)

18 August 2017

PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2 (English)

1 reference

18 August 2017

Nikolaos Patsoukis

1

1 reference

18 August 2017

Lequn Li

2

1 reference

18 August 2017

Duygu Sari

3

1 reference

18 August 2017

Victoria Petkova

4

1 reference

18 August 2017

Vassiliki A Boussiotis

5

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18 August 2017

language of work or name

English

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publication date

3 June 2013

1 reference

Molecular and Cellular Biology

18 August 2017

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18 August 2017

33

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18 August 2017

3091-3098

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18 August 2017

16

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describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3753920/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The PD-1 pathway in tolerance and autoimmunity

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PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

14 September 2017

1 reference

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PD-1 signaling in primary T cells

14 September 2017

1 reference

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Essential role for nuclear PTEN in maintaining chromosomal integrity

14 September 2017

1 reference

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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

14 September 2017

1 reference

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CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

14 September 2017

1 reference

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The biology and clinical relevance of the PTEN tumor suppressor pathway

14 September 2017

1 reference

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Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses

14 September 2017

1 reference

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

14 September 2017

1 reference

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Direct identification of PTEN phosphorylation sites

14 September 2017

1 reference

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The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

14 September 2017

1 reference

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Phosphorylation of the PTEN tail regulates protein stability and function

14 September 2017

1 reference

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

14 September 2017

1 reference

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The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

14 September 2017

1 reference

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753920

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

14 September 2017

1 reference

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

14 September 2017

1 reference

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PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753920

Selective effects of PD-1 on Akt and Ras pathways regulate molecular components of the cell cycle and inhibit T cell proliferation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753920

Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753920

Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells.

29 September 2017

1 reference

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Evidence for the induction of casein kinase II in bovine lymphocytes transformed by the intracellular protozoan parasite Theileria parva

29 September 2017

1 reference

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Expression of the casein kinase 2 subunits in Chinese hamster ovary and 3T3 L1 cells provides information on the role of the enzyme in cell proliferation and the cell cycle

29 September 2017

1 reference

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Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle.

27 June 2018

1 reference

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Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

27 June 2018

1 reference

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Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma.

3 September 2018

1 reference

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Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3753920

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

3 September 2018

1 reference

12 December 2020

Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated with poor clinical outcome

1 reference

12 December 2020

Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

1 reference

12 December 2020

Cell biological studies with monoclonal and polyclonal antibodies against human casein kinase II subunit beta demonstrate participation of the kinase in mitogenic signaling

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00319-13

1 reference

release_orqciu4w65ey3emu756jgyxucu

18 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/orqciu4w65ey3emu756jgyxucu

24 November 2022

mapped directly with Wikidata item

1 reference

18 August 2017

1 reference