Intrahepatic lymphocyte expression of dipeptidyl peptidase I-processed granzyme B and perforin induces hepatocyte expression of serine proteinase inhibitor 6 (Serpinb9/SPI-6). (Q37124811)

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English	Intrahepatic lymphocyte expression of dipeptidyl peptidase I-processed granzyme B and perforin induces hepatocyte expression of serine proteinase inhibitor 6 (Serpinb9/SPI-6).	scientific article

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Intrahepatic lymphocyte expression of dipeptidyl peptidase I-processed granzyme B and perforin induces hepatocyte expression of serine proteinase inhibitor 6 (Serpinb9/SPI-6). (English)

1 reference

Europe PubMed Central

18 August 2017

0 references

author name string

Heather W Stout-Delgado

1

1 reference

Europe PubMed Central

18 August 2017

Yonas Getachew

2

1 reference

Europe PubMed Central

18 August 2017

Bonnie C Miller

3

1 reference

Europe PubMed Central

18 August 2017

Dwain L Thiele

4

1 reference

Europe PubMed Central

18 August 2017

language of work or name

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publication date

1 November 2007

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Europe PubMed Central

18 August 2017

Journal of Immunology

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Europe PubMed Central

18 August 2017

179

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Europe PubMed Central

18 August 2017

10

1 reference

Europe PubMed Central

18 August 2017

6561-6567

1 reference

Europe PubMed Central

18 August 2017

The role of serpinb9/serine protease inhibitor 6 in preventing granzyme B-dependent hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654277

14 September 2017

Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654277

14 September 2017

Immunology of hepatitis B virus and hepatitis C virus infection

1 reference

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Fas and TNFR1, but not cytolytic granule-dependent mechanisms, mediate clearance of murine liver adenoviral infection

1 reference

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14 September 2017

CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

1 reference

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14 September 2017

Distribution of the human intracellular serpin protease inhibitor 8 in human tissues

1 reference

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14 September 2017

Type I interferons regulate inflammatory cell trafficking and macrophage inflammatory protein 1alpha delivery to the liver

1 reference

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Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

1 reference

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The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses

1 reference

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14 September 2017

The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654277

14 September 2017

Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo

1 reference

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A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9).

1 reference

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A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

1 reference

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Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis

1 reference

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1 reference

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14 September 2017

Serpin-6 expression protects embryonic stem cells from lysis by antigen-specific CTL.

1 reference

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Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation

1 reference

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Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions.

1 reference

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14 September 2017

Antiviral cytokines induce hepatic expression of the granzyme B inhibitors, proteinase inhibitor 9 and serine proteinase inhibitor 6.

1 reference

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14 September 2017

Granzyme B plays a critical role in cytotoxic lymphocyte-induced apoptosis

1 reference

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14 September 2017

Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms

1 reference

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29 September 2017

Dipeptidyl peptidase I is enriched in granules of in vitro- and in vivo-activated cytotoxic T lymphocytes.

1 reference

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27 June 2018

CD27-CD27 ligand/CD70 interactions enhance alloantigen-induced proliferation and cytolytic activity in CD8+ T lymphocytes.

1 reference

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Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

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3 September 2018

A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis

1 reference

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HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection

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Interferon alpha 2b decreases hepatic micrometastasis in a murine model of ocular melanoma by activation of intrinsic hepatic natural killer cells

1 reference

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Passive and active mechanisms trap activated CD8+ T cells in the liver.

1 reference

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Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

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Comparison of Human Chromosome 6p25 with Mouse Chromosome 13 Reveals a Greatly Expanded Ov-Serpin Gene Repertoire in the Mouse

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Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I

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Identifiers

10.4049/JIMMUNOL.179.10.6561

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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