Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy (Q37127322)

18 August 2017

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy (English)

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18 August 2017

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Jeffery D Molkentin

9

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author name string

Douglas P Millay

1

1 reference

18 August 2017

Michelle A Sargent

2

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18 August 2017

Hanna Osinska

3

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18 August 2017

Christopher P Baines

4

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18 August 2017

Elisabeth R Barton

5

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18 August 2017

Grégoire Vuagniaux

6

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18 August 2017

H Lee Sweeney

7

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18 August 2017

Jeffrey Robbins

8

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18 August 2017

language of work or name

English

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publication date

16 March 2008

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18 August 2017

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18 August 2017

14

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18 August 2017

4

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18 August 2017

442-447

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describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2655270/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm1736

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cites work

Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Muscle damage in mdx (dystrophic) mice: role of calcium and reactive oxygen species.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Defective membrane repair in dysferlin-deficient muscular dystrophy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

The mitochondrion in apoptosis: how Pandora's box opens

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Calcineurin activity is required for the initiation of skeletal muscle differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation By electron flow through the respiratory chain complex i.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2655270

Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM1736

Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18345011

12 December 2020

inferred from PubMed ID database lookup

Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18345011

12 December 2020

inferred from PubMed ID database lookup

A treadmill exercise regimen for identifying cardiovascular phenotypes in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18345011

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NM1736

1 reference

18 August 2017

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18 August 2017

1 reference