Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci (Q37129602)

18 August 2017

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci (English)

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18 August 2017

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4

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12 June 2020

Joseph M Replogle

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12 June 2020

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Philip L De Jager

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12 June 2020

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Elizabeth M Bradshaw

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12 June 2020

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Charles C White

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12 June 2020

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Lori B Chibnik

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12 June 2020

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David A Bennett

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12 June 2020

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Julie A Schneider

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12 June 2020

author name string

Gail Chan

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12 June 2020

Phoebe A Winn

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12 June 2020

Laura R Glick

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12 June 2020

Nicole E Cuerdon

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12 June 2020

Katie J Ryan

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12 June 2020

Keith A Johnson

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12 June 2020

Reisa A Sperling

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12 June 2020

language of work or name

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26 July 2016

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18 August 2017

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12 June 2020

volume

2

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12 June 2020

issue

4

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12 June 2020

page(s)

e90

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CD33 modulates TREM2: convergence of Alzheimer loci.

12 June 2020

cites work

1 reference

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The dynamics of monocytes and microglia in Alzheimer's disease

14 September 2017

1 reference

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ImmVar project: Insights and design considerations for future studies of "healthy" immune variation

14 September 2017

1 reference

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Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Genomic variation. Impact of regulatory variation from RNA to protein

14 September 2017

1 reference

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

14 September 2017

1 reference

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Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

14 September 2017

1 reference

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Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

14 September 2017

1 reference

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CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

14 September 2017

1 reference

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The role of innate and adaptive immunity in Parkinson's disease

14 September 2017

1 reference

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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Clinical presentation and differential diagnosis of dementia with Lewy bodies: a review

14 September 2017

1 reference

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TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

14 September 2017

1 reference

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Overview and findings from the rush Memory and Aging Project

14 September 2017

1 reference

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Overview and findings from the religious orders study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Nigral pathology and parkinsonian signs in elders without Parkinson disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

METAL: fast and efficient meta-analysis of genomewide association scans

14 September 2017

1 reference

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Mechanisms underlying inflammation in neurodegeneration

14 September 2017

1 reference

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Interface between tauopathies and synucleinopathies: A tale of two proteins

14 September 2017

1 reference

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Dimensionality of parkinsonian signs in aging and Alzheimer's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Convergent Genetic and Expression Datasets Highlight TREM2 in Parkinson's Disease Susceptibility

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages

14 September 2017

1 reference

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FcgammaR-mediated phagocytosis by human macrophages involves Hck, Syk, and Pyk2 and is augmented by GM-CSF.

29 September 2017

1 reference

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The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort.

27 June 2018

1 reference

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Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962525

10.1212/NXG.0000000000000090

3 September 2018

Identifiers

DOI

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12 June 2020

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12 June 2020

PubMed publication ID

27504496

1 reference