Stem cells for cardiovascular repair - the challenges of the aging heart (Q37132137)

18 August 2017

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title

Stem cells for cardiovascular repair - the challenges of the aging heart (English)

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18 August 2017

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Victoria L T Ballard

1

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PubMed ID

18396293

18 August 2017

Jay M Edelberg

series ordinal

2

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18 August 2017

4 March 2008

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Journal of Molecular and Cellular Cardiology

18 August 2017

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18 August 2017

45

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18 August 2017

4

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18 August 2017

582-592

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Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

18 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Isolation of putative progenitor endothelial cells for angiogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Adult cardiac stem cells are multipotent and support myocardial regeneration

7 January 2021

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The embryonic origins of hematopoietic stem cells: a tale of hemangioblast and hemogenic endothelium

7 January 2021

1 reference

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7 January 2021

Haemopoietic stem cells

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Transplantation of low dose CD34+KDR+ cells promotes vascular and muscular regeneration in ischemic limbs.

7 January 2021

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CD34+ blood cells accelerate vascularization and healing of diabetic mouse skin wounds

7 January 2021

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Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1

7 January 2021

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Molecular and secretory profiles of human mesenchymal stromal cells and their abilities to maintain primitive hematopoietic progenitors.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Adult mesenchymal stem cells: a pluripotent population with multiple applications

7 January 2021

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Mesenchymal stem cells are superior to angiogenic growth factor genes for improving myocardial performance in the mouse model of acute myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Effects of bone marrow derived mesenchymal stem cells transplantation in acutely infarcting myocardium.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

7 January 2021

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Endothelial progenitor cells for postnatal vasculogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration

7 January 2021

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Erythropoietin regulates endothelial progenitor cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Synergistic targeting with bone marrow-derived cells and PDGF improves diabetic vascular function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Cardiomyocytes can be generated from marrow stromal cells in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Bone marrow cells regenerate infarcted myocardium

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Mobilized bone marrow cells repair the infarcted heart, improving function and survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Human bone marrow-derived mesenchymal stem cells transplanted into damaged rabbit heart to improve heart function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Bone marrow Oct3/4+ cells differentiate into cardiac myocytes via age-dependent paracrine mechanisms

7 January 2021

1 reference

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

7 January 2021

1 reference

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

7 January 2021

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Induced pluripotent stem cell lines derived from human somatic cells

7 January 2021

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Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation

7 January 2021

1 reference

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Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages

7 January 2021

1 reference

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Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active Cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Niche-dependent translineage commitment of endothelial progenitor cells, not cell fusion in general, into myocardial lineage cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Targets for regulating angiogenesis in the ageing endothelium

7 January 2021

1 reference

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Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue.

7 January 2021

1 reference

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Isolation and characterization of a stem cell population from adult human liver

7 January 2021

1 reference

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Calcium signals induce liver stem cells to acquire a cardiac phenotype

7 January 2021

1 reference

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Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

7 January 2021

1 reference

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Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair

7 January 2021

1 reference

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Impaired progenitor cell activity in age-related endothelial dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse

7 January 2021

1 reference

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Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Telomerase activity in rat cardiac myocytes is age and gender dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Oxidative damage and age-related functional declines

7 January 2021

1 reference

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Life and death of cardiac stem cells: a paradigm shift in cardiac biology

7 January 2021

1 reference

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Autophagy in cardiac myocyte homeostasis, aging, and pathology

7 January 2021

1 reference

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Age-dependent impairment of angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Platelet-derived growth factor-AB limits the extent of myocardial infarction in a rat model: feasibility of restoring impaired angiogenic capacity in the aging heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Growth factor-mediated reversal of senescent dysfunction of ischemia-induced cardioprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Inhibited Angiogenesis in Aging: A Role for TIMP-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2008.02.277

Age-associated changes in cardiac matrix and integrins

7 January 2021

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Vascular tenascin-C regulates cardiac endothelial phenotype and neovascularization

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Gene therapy for myocardial angiogenesis

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Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia

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Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients.

7 January 2021

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Effects of Ad5FGF-4 in patients with angina: an analysis of pooled data from the AGENT-3 and AGENT-4 trials

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Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarction

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Effects of Granulocyte Colony Stimulating Factor on Functional Activities of Endothelial Progenitor Cells in Patients With Chronic Ischemic Heart Disease

7 January 2021

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Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI)

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Stem cell mobilization by granulocyte-colony-stimulating factor in acute myocardial infarction: lessons from the REVIVAL-2 trial

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HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

7 January 2021

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Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

7 January 2021

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Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition

7 January 2021

1 reference

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Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells

7 January 2021

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Endothelial progenitor cell mobilization and increased intravascular nitric oxide in patients undergoing cardiac rehabilitation

7 January 2021

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Simvastatin enhances endothelial differentiation of peripheral blood mononuclear cells in hypercholesterolemic patients and induces pro-angiogenic cytokine IL-8 secretion from monocytes

7 January 2021

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Harnessing hormonal signaling for cardioprotection

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Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group

7 January 2021

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Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

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Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

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Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans

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Bone marrow cell transfer in acute myocardial infarction

7 January 2021

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Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI).

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Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

7 January 2021

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Autologous stem cell transplantation in acute myocardial infarction: The ASTAMI randomized controlled trial. Intracoronary transplantation of autologous mononuclear bone marrow cells, study design and safety aspects

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Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction

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Stem cell therapy in postinfarction chronic coronary heart disease

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Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure

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Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial

7 January 2021

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Bone-marrow-derived cell transfer after ST-elevation myocardial infarction: lessons from the BOOST trial

7 January 2021

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Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis

7 January 2021

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Antibody targeting of stem cells to infarcted myocardium.

7 January 2021

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Cells, scaffolds, and molecules for myocardial tissue engineering

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Autologous bone-marrow stem-cell transplantation for myocardial regeneration

7 January 2021

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Pilot study to evaluate the safety and feasibility of intracoronary CD133(+) and CD133(-) CD34(+) cell therapy in patients with nonviable anterior myocardial infarction.

7 January 2021

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Safety analysis and improved cardiac function following local autologous transplantation of CD133(+) enriched bone marrow cells after myocardial infarction

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The roles of telomeres and telomerase in cell life span

7 January 2021

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7 January 2021

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Identifiers

DOI

10.1016/J.YJMCC.2008.02.277

1 reference

18 August 2017

1 reference

PubMed ID

18396293