Lessons from transgenic and knockout animals about noninsulin-dependent diabetes mellitus (Q37136381)

18 August 2017

Lessons from transgenic and knockout animals about noninsulin-dependent diabetes mellitus (English)

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18 August 2017

2

Kahn CR

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18 August 2017

Patti ME

1

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18 August 2017

1 November 1996

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Trends in Endocrinology and Metabolism

18 August 2017

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18 August 2017

7

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18 August 2017

9

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18 August 2017

311-319

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Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

18 August 2017

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Impaired insulin signaling in skeletal muscles from transgenic mice expressing kinase-deficient insulin receptors

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Calmodulin-induced early-onset diabetes in transgenic mice

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Pancreatic islet GLUT2 glucose transporter mRNA and protein expression in humans with and without NIDDM.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Genetic analysis of obesity-induced diabetes associated with a limited capacity to synthesize insulin in C57BL/KS mice: evidence for polygenic control.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Regulatory role of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic beta cells. Enhanced insulin secretion in CD38-expressing transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Gene modification via "plug and socket" gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Glucose uptake in human adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Insulin action impaired by deficiency of the G-protein subunit G ialpha2

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Transgenic mice for the study of diabetes mellitus.

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https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Transgenic mice overproducing islet amyloid polypeptide have increased insulin storage and secretion in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2896%2900154-3

7 January 2021

10.1016/S1043-2760(96)00154-3

Identifiers

DOI

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18 August 2017

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PubMed ID

18406764