A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis. (Q37142451)

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scientific article published on July 2013

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English	A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis.	scientific article published on July 2013

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scholarly article

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23 February 2020

A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis (English)

1 reference

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23 February 2020

7

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23 February 2020

author name string

W C Ports

1

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23 February 2020

S Khan

2

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23 February 2020

S Lan

3

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23 February 2020

M Lamba

4

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23 February 2020

C Bolduc

5

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23 February 2020

R Bissonnette

6

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23 February 2020

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publication date

1 July 2013

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23 February 2020

British Journal of Dermatology

1 reference

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23 February 2020

169

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23 February 2020

1

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23 February 2020

137-145

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23 February 2020

Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

Progress in understanding the immunopathogenesis of psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

The JAK-STAT signaling pathway: input and output integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

6 September 2017

Molecular pathophysiology of psoriasis and molecular targets of antipsoriatic therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

27 June 2018

Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

Treatment of plaque psoriasis with the two-compound product calcipotriol/betamethasone dipropionate versus both monotherapies: an immunohistochemical study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3761190

3 September 2018

Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigator-masked comparison of the efficacy and safety of twice daily applications of calcitriol 3 microg/g ointment vs. calcipotriol 50 microg/g ointment in subjects with mild to moderate chronic plaque-type psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tofacitinib or Adalimumab versus Placebo in Rheumatoid Arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Once daily treatment of psoriasis with tacalcitol compared with twice daily treatment with calcipotriol. A double-blind trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canadian guidelines for the management of plaque psoriasis: overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New biologic drugs get under the skin of psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23387374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BJD.12266

1 reference

Europe PubMed Central

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23 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23387374%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23387374%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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