Everything you wanted to know about small RNA but were afraid to ask. (Q37144092)

18 August 2017

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title

Everything you wanted to know about small RNA but were afraid to ask. (English)

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18 August 2017

Scott D Boyd

1

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18 August 2017

21 April 2008

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18 August 2017

Laboratory Investigation

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18 August 2017

88

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18 August 2017

6

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18 August 2017

569-578

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https://scigraph.springernature.com/pub.10.1038/labinvest.2008.32

18 August 2017

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Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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Targeted mRNA degradation by double-stranded RNA in vitro

21 January 2018

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A species of small antisense RNA in posttranscriptional gene silencing in plants

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Identification of hundreds of conserved and nonconserved human microRNAs

21 January 2018

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Diversity of microRNAs in human and chimpanzee brain

21 January 2018

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Global identification of human transcribed sequences with genome tiling arrays

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An atlas of human gene expression from massively parallel signature sequencing (MPSS).

21 January 2018

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Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution

21 January 2018

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21 January 2018

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The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint

21 January 2018

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The expansion of the metazoan microRNA repertoire

21 January 2018

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Trans-splicing and polyadenylation of let-7 microRNA primary transcripts

21 January 2018

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MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

RNA polymerase III transcribes human microRNAs

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification of mammalian microRNA host genes and transcription units

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Specificity of microRNA target selection in translational repression

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Human let-7a miRNA blocks protein production on actively translating polyribosomes

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Evidence that microRNAs are associated with translating messenger RNAs in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNAs direct rapid deadenylation of mRNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA silencing through RISC recruitment of eIF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNAs repress translation of m7Gppp-capped target mRNAs in vitro by inhibiting initiation and promoting deadenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Switching from repression to activation: microRNAs can up-regulate translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

miRBase: microRNA sequences, targets and gene nomenclature

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Myostatin: a modulator of skeletal-muscle stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Induction and suppression of RNA silencing: insights from viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A mammalian microRNA expression atlas based on small RNA library sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNAs regulate brain morphogenesis in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Embryonic stem cell-specific MicroRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Human embryonic stem cells express a unique set of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Stem cell division is regulated by the microRNA pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Characterization of Dicer-deficient murine embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Critical roles for Dicer in the female germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Myogenic factors that regulate expression of muscle-specific microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA-133 controls cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

miR-181a is an intrinsic modulator of T cell sensitivity and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Dynamic regulation of miRNA expression in ordered stages of cellular development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Regulation of the germinal center response by microRNA-155

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Requirement of bic/microRNA-155 for normal immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA expression dynamics during murine and human erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Analysis of short RNAs in the malaria parasite and its red blood cell host.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Noncoding RNAs in the mammalian central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification of tissue-specific microRNAs from mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A functional study of miR-124 in the developing neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Patterns of known and novel small RNAs in human cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A microRNA polycistron as a potential human oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Impaired microRNA processing enhances cellular transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

High-throughput microRNAome analysis in human germ cell tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Widespread deregulation of microRNA expression in human prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA expression profiling in classic Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Control of stress-dependent cardiac growth and gene expression by a microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification of microRNAs of the herpesvirus family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification of virus-encoded microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Host immune system gene targeting by a viral miRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

A cellular microRNA mediates antiviral defense in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

The Ebola virus VP35 protein is a suppressor of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

MicroRNA-155 is induced during the macrophage inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Construction of small RNA cDNA libraries for deep sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Analysis of microRNA expression by in situ hybridization with RNA oligonucleotide probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

miChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

Splicing of messenger RNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

A germline-specific class of small RNAs binds mammalian Piwi proteins

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

Detection of microRNAs by Northern blot analyses using LNA probes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

Profiling of microRNA expression by mRAP

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

Mustering the micromanagers

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2008.32

7 January 2021

10.1038/LABINVEST.2008.32

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18427554