Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells (Q37155498)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240024%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells (English)

1 reference

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22 January 2020

1 reference

GOA release 2020-03-11

author

Concepción Lillo

4

1 reference

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22 January 2020

Michael S. Marks

6

1 reference

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22 January 2020

author name string

Monika Damek-Poprawa

1

1 reference

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22 January 2020

Tanja Diemer

2

1 reference

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22 January 2020

Vanda S Lopes

3

1 reference

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22 January 2020

Dawn C Harper

5

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22 January 2020

Yalin Wu

7

1 reference

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22 January 2020

Janet R Sparrow

8

1 reference

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22 January 2020

Rivka A Rachel

9

1 reference

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22 January 2020

David S Williams

10

1 reference

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22 January 2020

Kathleen Boesze-Battaglia

11

1 reference

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22 January 2020

language of work or name

English

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publication date

23 February 2009

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Journal of Biological Chemistry

22 January 2020

published in

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22 January 2020

volume

284

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22 January 2020

issue

16

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22 January 2020

page(s)

10877-10889

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240024%20AND%20SRC:MED&resulttype=core&format=json

Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism

22 January 2020

cites work

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The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator

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6 September 2017

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6 September 2017

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Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis

6 September 2017

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Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate

6 September 2017

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RPE lipofuscin and its role in retinal pathobiology

6 September 2017

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Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.

6 September 2017

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dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice

6 September 2017

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Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.

6 September 2017

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The building BLOC(k)s of lysosomes and related organelles

6 September 2017

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Isolation and culture of primary mouse retinal pigmented epithelial cells.

6 September 2017

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RP1 is required for the correct stacking of outer segment discs

6 September 2017

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PI3P signaling regulates receptor sorting but not transport in the endosomal pathway

6 September 2017

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Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein

6 September 2017

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Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model

6 September 2017

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The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

6 September 2017

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Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

6 September 2017

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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

6 September 2017

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When lysosomes get old.

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Regulated secretion from hemopoietic cells

6 September 2017

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Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D

6 September 2017

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6 September 2017

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Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes

6 September 2017

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The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR)

6 September 2017

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ARPE-19, a human retinal pigment epithelial cell line with differentiated properties

6 September 2017

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The murine dilute suppressor gene encodes a cell autonomous suppressor

6 September 2017

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Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum

6 September 2017

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Participation of the retinal pigment epithelium in the rod outer segment renewal process

6 September 2017

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The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln

6 September 2017

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Dilute suppressor dsu acts semidominantly to suppress the coat color phenotype of a deletion mutation, dl20J, of the murine dilute locus

6 September 2017

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Trafficking of lysosomal enzymes in normal and disease states

6 September 2017

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Lysosomal enzymes and their receptors

6 September 2017

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The biogenesis of lysosomes

6 September 2017

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Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations

6 September 2017

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Lysosomal dysfunctions associated with mutations at mouse pigment genes

6 September 2017

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Regional variation and age-related changes of lysosomal enzymes in the human retinal pigment epithelium

6 September 2017

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A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity

14 September 2017

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Analysis of the rate of disk membrane digestion by cultured RPE cells

14 September 2017

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Chondrocytes utilize a cholesterol-dependent lipid translocator to externalize phosphatidylserine

14 September 2017

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Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus.

14 September 2017

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Studies on the retina and the pigment epithelium in hereditary canine ceroid lipofuscinosis. II. The subcellular distribution of lysosomal hydrolases and other enzymes

14 September 2017

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A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors

14 September 2017

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Modulation of cathepsin D activity in retinal pigment epithelial cells

27 June 2018

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Structural requirements of procathepsin D activation and maturation

27 June 2018

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Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

27 June 2018

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Vectorial accumulation of cathepsin D in retinal pigmented epithelium: effects of age

27 June 2018

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Accumulation of oxidized lipid-protein complexes alters phagosome maturation in retinal pigment epithelium

27 June 2018

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Products of lipid peroxidation induce missorting of the principal lysosomal protease in retinal pigment epithelium

3 September 2018

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Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration

3 September 2018

1 reference

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p16(Ink4a) in melanocyte senescence and differentiation.

3 September 2018

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Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin

3 September 2018

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Oxidized low density lipoprotein-induced inhibition of processing of photoreceptor outer segments by RPE.

3 September 2018

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3 September 2018

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Hyperlipofuscinosis and subretinal fibrosis in Stargardt's disease.

3 September 2018

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Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction

3 September 2018

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Immortalization of polarized rat retinal pigment epithelium.

3 September 2018

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TAM receptor function in the retinal pigment epithelium

3 September 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M808857200

Degradation of Rod Outer Segment Proteins by Cathepsin D

21 January 2018

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12 December 2020

Rod outer segment disk shedding in rat retina: relationship to cyclic lighting

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12 December 2020

Circadian nature of rod outer segment disc shedding in the rat

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12 December 2020

Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues

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12 December 2020

Degradation of rhodopsin by a lysosomal fraction of retinal pigment epithelium: biochemical aspects of the visual process. XLI

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A histopathologic study of Best's macular dystrophy

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Monoclonal antibodies to rhodopsin: characterization, cross-reactivity, and application as structural probes

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Dilute suppressor, a new suppressor gene in the house mouse

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Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells

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Accumulation of inactive cathepsin D in old rats

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12 December 2020

The fate of the phagosome: conversion to 'age pigment' and impact in human retinal pigment epithelium

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Visual cells and the concept of renewal

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Enzymatic deglycosylation of bovine rhodopsin

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Proteolytic processing of cathepsin D in prelysosomal organelles

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12 December 2020

Detection and possible functions of a cysteine protease involved in digestion of rod outer segments by retinal pigment epithelial cells

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12 December 2020

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12 December 2020

Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin

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12 December 2020

FROM CYTASES TO LYSOSOMES

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12 December 2020

Phosphoinositides' link to neurodegeneration.

1 reference

12 December 2020

The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane

1 reference

12 December 2020

Does A2E, a retinoid component of lipofuscin and inhibitor of lysosomal degradative functions, directly affect the activity of lysosomal hydrolases?

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12 December 2020

Identifiers

DOI

10.1074/JBC.M808857200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240024%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240024%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

19240024

1 reference