Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer (Q37164282)

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scientific article published on June 2008

Language	Label	Description	Also known as
English	Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer	scientific article published on June 2008

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer (English)

1 reference

Europe PubMed Central

18 August 2017

apoptotic process

0 references

pancreatic cancer

1 reference

based on heuristic

inferred from title

Fazlul H. Sarkar

6

object named as

Fazlul H Sarkar

1 reference

Europe PubMed Central

18 August 2017

author name string

Shadan Ali

1

1 reference

Europe PubMed Central

18 August 2017

Sanjeev Banerjee

2

1 reference

Europe PubMed Central

18 August 2017

Aamir Ahmad

3

1 reference

Europe PubMed Central

18 August 2017

Bassel F El-Rayes

4

1 reference

Europe PubMed Central

18 August 2017

Philip A Philip

5

1 reference

Europe PubMed Central

18 August 2017

publication date

1 June 2008

1 reference

Europe PubMed Central

18 August 2017

Molecular Cancer Therapeutics

1 reference

Europe PubMed Central

18 August 2017

7

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Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

1708-1719

1 reference

Europe PubMed Central

18 August 2017

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

1 reference

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Intracellular pattern recognition receptors in the host response

1 reference

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6 September 2017

Nuclear factor-kappaB in cancer development and progression

1 reference

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6 September 2017

NF-kappaB and cancer: mechanisms and targets

1 reference

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6 September 2017

Tyrosine kinase inhibitors and gemcitabine: new treatment options in pancreatic cancer?

1 reference

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6 September 2017

Cancer statistics, 2006

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

6 September 2017

A review of systemic therapy for advanced pancreatic cancer

1 reference

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6 September 2017

Prostaglandins and cancer

1 reference

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6 September 2017

Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II Trial

1 reference

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6 September 2017

Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

6 September 2017

3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression

1 reference

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6 September 2017

Akt is a downstream target of NF-kappa B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

6 September 2017

3,3'-diindolylmethane, a major condensation product of indole-3-carbinol, is a potent estrogen in the rainbow trout

1 reference

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

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A review of mechanisms underlying anticarcinogenicity by brassica vegetables

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6 September 2017

Vegetables, fruit, and cancer. I. Epidemiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

6 September 2017

Inhibition of angiogenesis and invasion by 3,3'-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Prostaglandin E2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells

1 reference

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Targeting BCL-2 overexpression in various human malignancies through NF-kappaB inhibition by the proteasome inhibitor bortezomib

1 reference

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14 September 2017

Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kappaB pathways in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

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Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines

1 reference

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14 September 2017

Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Apoptosis-inducing effect of chemotherapeutic agents is potentiated by soy isoflavone genistein, a natural inhibitor of NF-kappaB in BxPC-3 pancreatic cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

14 September 2017

Indole-3-carbinol (I3C) induces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

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Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

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Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

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Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

1 reference

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28 September 2017

Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.

1 reference

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28 September 2017

NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

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28 September 2017

Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

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27 June 2018

Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent.

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27 June 2018

Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol.

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27 June 2018

Oligomerization of indole-3-carbinol in aqueous acid

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27 June 2018

Multiple, disparate roles for calcium signaling in apoptosis of human prostate and cervical cancer cells exposed to diindolylmethane.

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3 September 2018

3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

3 September 2018

Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770536

3 September 2018

Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells

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https://pubmed.ncbi.nlm.nih.gov/18566242

12 December 2020

based on heuristic

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Epidermal growth factor receptor expression in human pancreatic cancer: Significance for liver metastasis

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https://pubmed.ncbi.nlm.nih.gov/18566242

12 December 2020

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Frequent expression of genes for receptor tyrosine kinases and their ligands in human pancreatic cancer cells

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12 December 2020

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Developments in the systemic therapy of pancreatic cancer

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9 February 2024

https://opencitations.net/index/api/v1/references/10.1158/1535-7163.MCT-08-0354

Identifiers

10.1158/1535-7163.MCT-08-0354

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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