Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies. (Q37179384)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18518759%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies (English)

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8 January 2020

2

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8 January 2020

author name string

Amanda K Beck

series ordinal

1

1 reference

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8 January 2020

Michele Carbone

series ordinal

3

1 reference

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8 January 2020

Haining Yang

series ordinal

4

1 reference

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8 January 2020

language of work or name

English

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publication date

1 June 2008

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8 January 2020

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8 January 2020

volume

4

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8 January 2020

issue

3

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8 January 2020

page(s)

341-349

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Ranpirnase--an antitumour ribonuclease: its potential role in malignant mesothelioma

8 January 2020

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Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnase

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Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity

21 January 2018

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Atomic resolution structures of ribonuclease A at six pH values

21 January 2018

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Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity

21 January 2018

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Enzymatic and structural characterisation of amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes

21 January 2018

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Contribution of structural peculiarities of onconase to its high stability and folding kinetics

21 January 2018

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Ribonuclease inhibitor: structure and function

21 January 2018

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Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A

21 January 2018

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Structural Basis for Catalysis by Onconase

21 January 2018

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Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma

21 January 2018

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Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family

21 January 2018

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Transfer RNA cleavages by onconase reveal unusual cleavage sites.

21 January 2018

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Cytotoxic Ribonucleases and RNA Interference (RNAi)

21 January 2018

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Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase).

21 January 2018

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Onconase induces caspase-independent cell death in chemoresistant neuroblastoma cells

21 January 2018

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Phase II trial of a single weekly intravenous dose of ranpirnase in patients with unresectable malignant mesothelioma

21 January 2018

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Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines

21 January 2018

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Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease.

21 January 2018

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Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase.

21 January 2018

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Glycosylation of onconase increases its conformational stability and toxicity for cancer cells.

21 January 2018

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TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis

21 January 2018

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Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase.

21 January 2018

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G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation

21 January 2018

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Mechanisms of enhanced tumoricidal efficacy of multiple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer

21 January 2018

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A Study of the Intracellular Routing of Cytotoxic Ribonucleases

21 January 2018

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A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease

21 January 2018

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Eighth International Mesothelioma Interest Group

21 January 2018

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