Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer by orchestration of oligosaccharide and polypeptide domains. (Q37186518)

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scientific article published on March 2009

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English	Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer by orchestration of oligosaccharide and polypeptide domains.	scientific article published on March 2009

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scholarly article

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22 January 2020

Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer by orchestration of oligosaccharide and polypeptide domains (English)

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22 January 2020

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based on heuristic

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oligosaccharide

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based on heuristic

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1 reference

based on heuristic

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2

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22 January 2020

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Jianglong Zhu

1

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22 January 2020

Govind Ragupathi

3

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22 January 2020

Constantine M George

4

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22 January 2020

Philip O Livingston

5

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22 January 2020

Samuel J Danishefsky

6

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22 January 2020

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1 March 2009

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22 January 2020

Journal of the American Chemical Society

1 reference

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22 January 2020

131

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22 January 2020

11

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22 January 2020

4151-4158

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19253940%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Synthesis of Human Cancer Associated Globo-H (MBr1) Glycosylamino Acid: Some Mechanistic and Conformational Reinvestigations

1 reference

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Robust immune responses elicited by a fully synthetic three-component vaccine

1 reference

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Humoral immune response to MUC5AC in patients with colorectal polyps and colorectal carcinoma

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6 September 2017

Synthetic carbohydrate-based antitumor vaccines: challenges and opportunities

1 reference

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6 September 2017

Prospects for total synthesis: a vision for a totally synthetic vaccine targeting epithelial tumors

1 reference

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6 September 2017

Emerging strategies in tumor vaccines.

1 reference

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6 September 2017

Novel target antigens for dendritic cell-based immunotherapy against ovarian cancer

1 reference

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6 September 2017

Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.

1 reference

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6 September 2017

Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial

1 reference

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From the Laboratory to the Clinic: A Retrospective on Fully Synthetic Carbohydrate-Based Anticancer Vaccines Frequently used abbreviations are listed in the appendix

1 reference

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6 September 2017

Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man.

1 reference

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6 September 2017

Concepts and principles of O-linked glycosylation

1 reference

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6 September 2017

Separation of positional isomers of oligosaccharides and glycopeptides by high-performance anion-exchange chromatography with pulsed amperometric detection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

6 September 2017

Cancer vaccines targeting carbohydrate antigens

1 reference

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14 September 2017

Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates

1 reference

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14 September 2017

Definition of an immunogenic region within the ovarian tumor antigen stratum corneum chymotryptic enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

14 September 2017

Immunization of ovarian cancer patients with a synthetic Lewis(y)-protein conjugate vaccine: a phase 1 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

28 September 2017

Mucin gene expression in ovarian cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

28 September 2017

Augmenting the immunogenicity of carbohydrate tumor antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

28 September 2017

Glycoconjugates facing the outside world

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

28 September 2017

Expression of the verotoxin receptor glycolipid, globotriaosylceramide, in ovarian hyperplasias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

26 June 2018

Synthetic vaccines consisting of tumor-associated MUC1 glycopeptide antigens and a T-cell epitope for the induction of a highly specific humoral immune response

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679991

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Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin

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Biomimetic synthesis of the tumor-associated (2,3)-sialyl-T antigen and its incorporation into glycopeptide antigens from the mucins MUC1 and MUC4.

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Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens

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1 reference

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Globotriaosyl ceramide (Gb3) expression in human tumour cells: intracellular trafficking defines a new retrograde transport pathway from the cell surface to the nucleus, which correlates with sensitivity to verotoxin.

1 reference

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Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides

1 reference

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Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance

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1 reference

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Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic vaccines of tumor-associated glycopeptide antigens by immune-compatible thioether linkage to bovine serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally processed class II epitope from the tumor antigen MUC1 primes human CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serological and immunochemical analysis of Lewis y (Ley) blood group antigen expression in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmenting the immunogenicity of synthetic MUC1 peptide vaccines in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High performance anion exchange chromatography of reduced oligosaccharides from sialomucins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second generation synthesis of the MBr1 (globo-H) breast tumor antigen: new application of the n-pentenyl glycoside method for achieving complex carbohydrate protein linkages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19253940

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA810147J

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Europe PubMed Central

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22 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

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22 January 2020

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