Immunity to malaria: more questions than answers (Q37194482)

18 August 2017

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title

Immunity to malaria: more questions than answers (English)

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18 August 2017

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Francis M Ndungu

2

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Jean Langhorne

object named as

Jean Langhorne

series ordinal

1

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Kevin Marsh

series ordinal

4

object named as

Kevin Marsh

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18 August 2017

Anne-Marit Sponaas

3

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PubMed ID

18563083

18 August 2017

language of work or name

English

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publication date

1 July 2008

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18 August 2017

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18 August 2017

9

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18 August 2017

7

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18 August 2017

725-732

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A novel antibody-dependent cellular cytotoxicity mechanism involved in defense against malaria requires costimulation of monocytes FcgammaRII and FcgammaRIII.

18 August 2017

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Differential Induction of TGF-β Regulates Proinflammatory Cytokine Production and Determines the Outcome of Lethal and NonlethalPlasmodium yoeliiInfections

21 January 2018

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CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway

21 January 2018

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Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.

21 January 2018

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Systemic tumor necrosis factor generated during lethal Plasmodium infections impairs dendritic cell function.

21 January 2018

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Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells

21 January 2018

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Plasmodium yoelii can ablate vaccine-induced long-term protection in mice.

21 January 2018

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Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effect

21 January 2018

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The global distribution of clinical episodes of Plasmodium falciparum malaria

21 January 2018

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7 January 2021

The past, present and future of childhood malaria mortality in Africa

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7 January 2021

Characterization of the antibody response against Plasmodium falciparum erythrocyte membrane protein 1 in human volunteers

1 reference

7 January 2021

Malaria, intestinal parasites, and schistosomiasis among Barawan Somali refugees resettling to the United States: a strategy to reduce morbidity and decrease the risk of imported infections.

1 reference

7 January 2021

Immunity to non-cerebral severe malaria is acquired after one or two infections

1 reference

7 January 2021

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

1 reference

7 January 2021

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

1 reference

7 January 2021

Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

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7 January 2021

A role for B cells in the development of T cell helper function in a malaria infection in mice

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7 January 2021

Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum

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7 January 2021

Gamma-globulin and acquired immunity to human malaria.

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7 January 2021

Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.

1 reference

7 January 2021

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

1 reference

7 January 2021

Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages

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7 January 2021

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.

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7 January 2021

The importance of human FcgammaRI in mediating protection to malaria

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7 January 2021

Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites.

1 reference

7 January 2021

Profiling the antibody immune response against blood stage malaria vaccine candidates.

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7 January 2021

Assessment of antibody protection against malaria sporozoites must be done by mosquito injection of sporozoites

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7 January 2021

Cytokine responses of CD4+ T cells during a Plasmodium chabaudi chabaudi (ER) blood-stage infection in mice initiated by the natural route of infection

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7 January 2021

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

1 reference

7 January 2021

Indicators of life-threatening malaria in African children

1 reference

7 January 2021

Does endotoxin cause both the disease and parasite death in acute malaria and babesiosis?

1 reference

7 January 2021

Tumour necrosis factor, fever and fatality in falciparum malaria

1 reference

7 January 2021

Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy con

1 reference

7 January 2021

Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria

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7 January 2021

Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India.

1 reference

7 January 2021

Low plasma concentrations of interleukin-10 in severe malarial anaemia compared with cerebral and uncomplicated malaria.

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7 January 2021

Increased levels of inflammatory mediators in children with severe Plasmodium falciparum malaria with respiratory distress

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7 January 2021

Low levels of RANTES are associated with mortality in children with cerebral malaria

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7 January 2021

Is there a future for TNF promoter polymorphisms?

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7 January 2021

Immunogenetic control of antibody responsiveness in a malaria endemic area

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7 January 2021

Description of three new polymorphisms in the intronic and 3'UTR regions of the human interferon gamma gene.

1 reference

7 January 2021

Functional analysis of a promoter variant of the gene encoding the interferon-gamma receptor chain I.

1 reference

7 January 2021

The cytokine balance in severe malarial anemia.

1 reference

7 January 2021

Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies

1 reference

7 January 2021

Insights into the immunopathogenesis of malaria using mouse models

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7 January 2021

Malarial anemia: of mice and men.

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7 January 2021

Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria

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7 January 2021

Innate immunity to malaria

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7 January 2021

Interactions between malaria parasites and the host immune system

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7 January 2021

TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells

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7 January 2021

Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1.

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7 January 2021

CD36 is a sensor of diacylglycerides

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7 January 2021

Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells.

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7 January 2021

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity

1 reference

7 January 2021

Stimulation of innate immune responses by malarial glycosylphosphatidylinositol via pattern recognition receptors.

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7 January 2021

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

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7 January 2021

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

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7 January 2021

MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

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7 January 2021

Murine cerebral malaria development is independent of toll-like receptor signaling

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7 January 2021

Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy

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7 January 2021

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

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7 January 2021

Virulence in rodent malaria: host genotype by parasite genotype interactions.

1 reference

7 January 2021

Is immunity to malaria really short-lived?

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7 January 2021

IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life

1 reference

7 January 2021

Human immune responses to the Plasmodium falciparum ring-infected erythrocyte surface antigen (Pf155/RESA) after a decrease in malaria transmission in Madagascar.

1 reference

7 January 2021

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area

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7 January 2021

Swift development of protective effector functions in naive CD8(+) T cells against malaria liver stages

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7 January 2021

Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance.

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7 January 2021

CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.

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7 January 2021

IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages.

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7 January 2021

Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites

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7 January 2021

IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites.

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7 January 2021

Impairment of humoral immunity to Plasmodium falciparum malaria in pregnancy by HIV infection

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7 January 2021

Direct activation of dendritic cells by the malaria parasite, Plasmodium chabaudi chabaudi.

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7 January 2021

Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells

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7 January 2021

Inhibition of dendritic cell maturation by malaria is dose dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1

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7 January 2021

Malaria blood stage suppression of liver stage immunity by dendritic cells

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7 January 2021

Peripheral blood dendritic cells in children with acute Plasmodium falciparum malaria.

1 reference

7 January 2021

The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection

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7 January 2021

Th1 memory: implications for vaccine development

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7 January 2021

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

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7 January 2021

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7 January 2021

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

7 January 2021

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

7 January 2021

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

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7 January 2021

Immune effector mechanisms in malaria

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7 January 2021

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

1 reference

7 January 2021

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

1 reference

7 January 2021

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

7 January 2021

Toll signaling: the TIReless quest for specificity

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7 January 2021

Recognition and signaling by toll-like receptors.

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7 January 2021

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

1 reference

7 January 2021

A role for CD36 in the regulation of dendritic cell function

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7 January 2021

Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells

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7 January 2021

Identifiers

DOI

10.1038/NI.F.205

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18 August 2017

1 reference

PubMed ID

18563083