MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation (Q37195241)

18 August 2017

MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation (English)

1 reference

18 August 2017

1 reference

Qian Wang

1

1 reference

18 August 2017

Richard Stump

series ordinal

2

1 reference

18 August 2017

John W McAvoy

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3

1 reference

18 August 2017

Frank J Lovicu

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4

1 reference

18 August 2017

language of work or name

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4 October 2008

1 reference

Experimental Eye Research

18 August 2017

1 reference

18 August 2017

88

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18 August 2017

2

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18 August 2017

293-306

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Akt signaling and cancer: surviving but not moving on.

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Mechanisms underlying differential responses to FGF signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Growth factor regulation of lens development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Structure, regulation and function of PKB/AKT--a major therapeutic target

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Localization of receptor-mediated signal transduction pathways: the inside story.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Body building: regulation of shape and size by PI3K/TOR signaling during development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

The tuberous sclerosis complex (TSC) pathway and mechanism of size control

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

The role of phosphoinositide 3-kinase lipid products in cell function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

6 September 2017

Phosphoinositide kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Platelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients with vitreoretinal disorders

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Use of vanadate as protein-phosphotyrosine phosphatase inhibitor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

PI3K: downstream AKTion blocks apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Differential effects of aqueous and vitreous on fiber differentiation and extracellular matrix accumulation in lens epithelial explants

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Wnt signaling enhances FGF2-triggered lens fiber cell differentiation.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Disruption of lens fiber cell differentiation and survival at multiple stages by region-specific expression of truncated FGF receptors.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

Spatial and temporal expression of p57(KIP2) during murine lens development.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683269

FGF signaling in chick lens development

3 September 2018

1 reference

12 December 2020

FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling

1 reference

12 December 2020

Influence of platelet-derived growth factor on lens epithelial cell proliferation and differentiation

1 reference

12 December 2020

Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation

1 reference

12 December 2020

Beta- and gamma-crystallin synthesis in rat lens epithelium explanted with neural retinal

1 reference

12 December 2020

Characterization of acidic and basic fibroblast growth factors in brain, retina and vitreous chick embryo

1 reference

12 December 2020

Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF)

1 reference

12 December 2020

Heterogeneity in localization of isoforms of TGF-beta in human retina, vitreous, and choroid

1 reference

12 December 2020

Acidic and basic FGF in ocular media and lens: implications for lens polarity and growth patterns

1 reference

12 December 2020

IGF-1 enhancement of FGF-induced lens fiber differentiation in rats of different ages

1 reference

12 December 2020

Localization of acidic fibroblast growth factor, basic fibroblast growth factor, and heparan sulphate proteoglycan in rat lens: implications for lens polarity and growth patterns

1 reference

12 December 2020

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

1 reference

12 December 2020

Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

12 December 2020

Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice

1 reference

12 December 2020

Expression of a truncated FGF receptor results in defective lens development in transgenic mice

1 reference

12 December 2020

FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens

1 reference

12 December 2020

IGF enhancement of FGF-induced fibre differentiation and DNA synthesis in lens explants

1 reference

12 December 2020

Presence of growth factor in human vitreous

1 reference

12 December 2020

LENS DEVELOPMENT: FIBER ELONGATION AND LENS ORIENTATION

1 reference

12 December 2020

Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling

1 reference

12 December 2020

Phosphatidylinositol 3-kinase is necessary for lens fiber cell differentiation and survival

1 reference

12 December 2020

Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate

1 reference

12 December 2020

Induction and maintenance of differentiation of rat lens epithelium by FGF-2, insulin and IGF-1

1 reference

12 December 2020

Synergism between temporally distinct growth factors: bFGF, insulin and lens cell differentiation

1 reference

12 December 2020

Insulin and IGF-I affect the protein composition of the lens fibre cell with possible consequences for cataract

1 reference

12 December 2020

10.1016/J.EXER.2008.08.023

Identifiers

DOI

1 reference

18 August 2017

1 reference

18 August 2017

1 reference