The two-faced NF-kappaB in the skin. (Q37198675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574737%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

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title

The two-faced NF-kappaB in the skin (English)

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9 January 2020

0 references

1

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9 January 2020

Maria H Ulvmar

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574737%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Rune Toftgård

series ordinal

3

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9 January 2020

publication date

1 July 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574737%20AND%20SRC:MED&resulttype=core&format=json

International Reviews of Immunology

9 January 2020

published in

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9 January 2020

volume

27

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9 January 2020

issue

4

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9 January 2020

page(s)

205-223

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Nuclear factor-kappaB in cancer development and progression

9 January 2020

cites work

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

21 January 2018

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Mechanisms regulating epithelial stratification

21 January 2018

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IKKalpha controls formation of the epidermis independently of NF-kappaB.

21 January 2018

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X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein

21 January 2018

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Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia

21 January 2018

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Gene defect in ectodermal dysplasia implicates a death domain adapter in development

21 January 2018

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Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice

21 January 2018

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Involvement of a novel Tnf receptor homologue in hair follicle induction.

21 January 2018

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The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains

21 January 2018

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The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms.

21 January 2018

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X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

21 January 2018

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Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

21 January 2018

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A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)

21 January 2018

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A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency

21 January 2018

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The same IkappaBalpha mutation in two related individuals leads to completely different clinical syndromes.

21 January 2018

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The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A

21 January 2018

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NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth

21 January 2018

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TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death

21 January 2018

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Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors

21 January 2018

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Sonic hedgehog signaling is essential for hair development

21 January 2018

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Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

21 January 2018

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Immunopathogenesis and role of T cells in psoriasis

21 January 2018

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Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

21 January 2018

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Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology.

21 January 2018

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Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

21 January 2018

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NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 January 2018

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

21 January 2018

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

21 January 2018

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Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.

21 January 2018

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Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

21 January 2018

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Transient suppression of macrophage functions by liposome-encapsulated drugs

21 January 2018

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Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis.

21 January 2018

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Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

21 January 2018

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p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice

21 January 2018

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

21 January 2018

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TGF-beta activated kinase-1: new insights into the diverse roles of TAK1 in development and immunity

21 January 2018

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Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

21 January 2018

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TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

21 January 2018

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TAK1 is a central mediator of NOD2 signaling in epidermal cells

21 January 2018

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NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.

21 January 2018

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Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

21 January 2018

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Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermis

21 January 2018

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NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

21 January 2018

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CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control

21 January 2018

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Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia

21 January 2018

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Codon 12 Harvey-ras mutations are rare events in non-melanoma human skin cancer

21 January 2018

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Low incidence of ras oncogene activation in human squamous cell carcinomas

21 January 2018

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Incontinentia pigmenti with painful subungual tumors: a two-generation study

21 January 2018

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Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management

21 January 2018

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Immune responsiveness and protective immunity after transplantation

21 January 2018

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180802130319

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

Negative regulation of JNK signaling by the tumor suppressor CYLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180802130319

10.1080/08830180802130319

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574737%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference