Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. (Q37201191)

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scientific article published on 19 August 2013

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English	Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons.	scientific article published on 19 August 2013

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7 March 2020

Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons (English)

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7 March 2020

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7 March 2020

Adam G Hendricks

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7 March 2020

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Erika L F Holzbaur

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7 March 2020

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Jacob E Lazarus

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7 March 2020

Keren Ben-Yaakov

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Tal Gradus

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7 March 2020

Mariko Tokito

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19 August 2013

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7 March 2020

Journal of Biological Chemistry

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7 March 2020

27812-27824

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7 March 2020

Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization

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Dynactin is required for transport initiation from the distal axon

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6 September 2017

Dynein tethers and stabilizes dynamic microtubule plus ends

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6 September 2017

Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters

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Regulated offloading of cytoplasmic dynein from microtubule plus ends to the cortex

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Immobilized pool of NCAM180 in the postsynaptic membrane is homeostatically replenished by the flux of NCAM180 from extrasynaptic regions.

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Neuromuscular junction defects in mice with mutation of dynein heavy chain 1.

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Regulators of the cytoplasmic dynein motor

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6 September 2017

Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells

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6 September 2017

Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon

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6 September 2017

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

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Microtubules in dendritic spine development

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Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin

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Microtubule plus-end tracking proteins in differentiated mammalian cells

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Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration

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6 September 2017

NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex.

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6 September 2017

Recruitment of dynein to the Jurkat immunological synapse

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6 September 2017

beta III spectrin binds to the Arp1 subunit of dynactin

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6 September 2017

The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex

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6 September 2017

E-MAP-115 (ensconsin) associates dynamically with microtubules in vivo and is not a physiological modulator of microtubule dynamics.

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Dynactin is required for microtubule anchoring at centrosomes

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Microtubule targeting of substrate contacts promotes their relaxation and dissociation

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6 September 2017

The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling.

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3 September 2018

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3 September 2018

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3 September 2018

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23960070

12 December 2020

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1 reference

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1 reference

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1 reference

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inferred from PubMed ID database lookup

Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice

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based on heuristic

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10.1074/JBC.M113.465088

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Europe PubMed Central

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7 March 2020

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Europe PubMed Central

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7 March 2020

PubMed publication ID

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Europe PubMed Central

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7 March 2020

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