APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation (Q37209158)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24026117%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation (English)

1 reference

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20 February 2020

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4

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20 February 2020

author name string

John S Poulton

series ordinal

1

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20 February 2020

Frank W Mu

series ordinal

2

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20 February 2020

David M Roberts

series ordinal

3

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20 February 2020

language of work or name

English

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publication date

11 September 2013

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20 February 2020

number of pages

11

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inferred from page(s)

published in

Development

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20 February 2020

volume

140

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20 February 2020

issue

20

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20 February 2020

page(s)

4226-4236

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describes a project that uses

20 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3787761/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Cortical actin dynamics facilitate early-stage centrosome separation

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6 September 2017

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Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?

6 September 2017

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The role of the APC tumor suppressor in chromosomal instability

6 September 2017

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Nuf, a Rab11 effector, maintains cytokinetic furrow integrity by promoting local actin polymerization

6 September 2017

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Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

6 September 2017

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6 September 2017

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APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

6 September 2017

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment

6 September 2017

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6 September 2017

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6 September 2017

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Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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How one becomes many: blastoderm cellularization in Drosophila melanogaster

6 September 2017

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Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

6 September 2017

1 reference

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DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Intestinal adenomas can develop with a stable karyotype and stable microsatellites

6 September 2017

1 reference

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Identification of a link between the tumour suppressor APC and the kinesin superfamily

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Continuous hematopoietic cell lines as model systems for leukemia-lymphoma research

6 September 2017

1 reference

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Asef, a link between the tumor suppressor APC and G-protein signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis

6 September 2017

1 reference

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Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

6 September 2017

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Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

6 September 2017

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Genetic instability in colorectal cancers

6 September 2017

1 reference

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Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras

6 September 2017

1 reference

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LKB1-mediated spatial control of GSK3beta and adenomatous polyposis coli contributes to centrosomal forward movement and neuronal migration in the developing neocortex.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

p53 is frequently mutated in Burkitt's lymphoma cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Centrosomes: CNN's broadcast reaches the cleavage furrow

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Mutations of the p53 gene in human myeloma cell lines

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos

26 June 2018

1 reference

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A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.

3 September 2018

1 reference

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Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

The significance of unstable chromosomes in colorectal cancer.

3 September 2018

1 reference

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Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787761

Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis

3 September 2018

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12 December 2020

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

12 December 2020

Molecular Genetics of Colorectal Cancer

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12 December 2020

The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimaerism

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12 December 2020

Identifiers

DOI

10.1242/DEV.094425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24026117%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24026117%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

24026117

1 reference