Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease (Q37219109)

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scientific article published on October 2013

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English	Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease	scientific article published on October 2013

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease (English)

1 reference

Europe PubMed Central

19 August 2017

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Alzheimer's disease

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author name string

Luqing Zhang

1

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Europe PubMed Central

19 August 2017

Panayiota Papadopoulos

2

1 reference

Europe PubMed Central

19 August 2017

Edith Hamel

3

1 reference

Europe PubMed Central

19 August 2017

language of work or name

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publication date

1 October 2013

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Europe PubMed Central

19 August 2017

British Journal of Pharmacology

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Europe PubMed Central

19 August 2017

170

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Europe PubMed Central

19 August 2017

3

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Europe PubMed Central

19 August 2017

661-670

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Europe PubMed Central

19 August 2017

Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-β and cerebrovascular pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792003

6 September 2017

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792003

6 September 2017

TRPV4 and the regulation of vascular tone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792003

6 September 2017

Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792003

6 September 2017

Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae

1 reference

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6 September 2017

TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity

1 reference

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Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel.

1 reference

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6 September 2017

Neurovascular function in Alzheimer's disease patients and experimental models

1 reference

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Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease

1 reference

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Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

1 reference

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6 September 2017

Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation

1 reference

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6 September 2017

Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels

1 reference

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Animal research: reporting in vivo experiments: the ARRIVE guidelines

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6 September 2017

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

1 reference

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6 September 2017

Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.

1 reference

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6 September 2017

Intact memory in TGF-β1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazone

1 reference

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Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo

1 reference

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Altered central TRPV4 expression and lipid raft association related to inappropriate vasopressin secretion in cirrhotic rats.

1 reference

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Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

1 reference

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6 September 2017

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792003

6 September 2017

The mechanosensitive nature of TRPV channels

1 reference

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Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime)

1 reference

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6 September 2017

Neurovascular regulation in the normal brain and in Alzheimer's disease

1 reference

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Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex

1 reference

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6 September 2017

TRPV4 calcium entry channel: a paradigm for gating diversity.

1 reference

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6 September 2017

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.

1 reference

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

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Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

1 reference

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6 September 2017

Endothelium-derived relaxing factor in brain blood vessels is not nitric oxide

1 reference

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6 September 2017

Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2.

1 reference

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Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation

1 reference

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Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease

1 reference

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Cardiac fibroblasts have functional TRPV4 activated by 4alpha-phorbol 12,13-didecanoate

1 reference

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Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

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PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries.

1 reference

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Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease.

1 reference

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Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium.

1 reference

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Potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species.

1 reference

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Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

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TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

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N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa

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21 January 2018

Transforming growth factor-beta 1 impairs endothelin-1-mediated contraction of brain vessels by inducing mitogen-activated protein (MAP) kinase phosphatase-1 and inhibiting p38 MAP kinase

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20 October 2018

Inflammatory factors are elevated in brain microvessels in Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/23889563

12 December 2020

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Mediation of endothelium-dependent relaxation: different response patterns in rat and rabbit basilar artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/23889563

12 December 2020

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SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23889563

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Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries

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https://pubmed.ncbi.nlm.nih.gov/23889563

12 December 2020

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Identifiers

10.1111/BPH.12315

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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