Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis (Q37226817)

19 August 2017

Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis (English)

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19 August 2017

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10

Kwok-Kin Wong

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19 August 2017

Leena Gandhi

1

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Ultan McDermott

object named as

Ultan McDermott

5

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author name string

Kate L McNamara

2

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19 August 2017

Danan Li

3

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19 August 2017

Christa L Borgman

4

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19 August 2017

Kathleyn A Brandstetter

6

1 reference

19 August 2017

Robert F Padera

7

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19 August 2017

Lucian R Chirieac

8

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19 August 2017

Jeffrey E Settleman

9

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19 August 2017

31 March 2009

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Cancer Prevention Research

19 August 2017

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19 August 2017

2

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19 August 2017

4

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19 August 2017

330-337

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describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2696128/fullTextXML

inferred from PubMed Central ID database lookup

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Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties

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Chemotherapy in addition to supportive care improves survival in advanced non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data from 16 randomized controlled trials

14 September 2017

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Antiangiogenic drugs and tyrosine kinases.

14 September 2017

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HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

14 September 2017

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Multicenter, phase II trial of sunitinib in previously treated, advanced non-small-cell lung cancer

14 September 2017

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

14 September 2017

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Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

14 September 2017

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Molecular basis for sunitinib efficacy and future clinical development

14 September 2017

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LKB1 modulates lung cancer differentiation and metastasis

14 September 2017

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Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1

14 September 2017

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Approval summary: sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma

14 September 2017

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Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial

14 September 2017

1 reference

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

14 September 2017

1 reference

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Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

14 September 2017

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Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer

14 September 2017

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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

14 September 2017

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Paracrine interactions of vascular endothelial growth factor and platelet-derived growth factor in endothelial and lung cancer cells.

14 September 2017

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Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy

14 September 2017

1 reference

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Vascular endothelial growth factor overexpression by soft tissue sarcoma cells: implications for tumor growth, metastasis, and chemoresistance

14 September 2017

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K-ras activation generates an inflammatory response in lung tumors

14 September 2017

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

14 September 2017

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Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21.

14 September 2017

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Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group

3 September 2018

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Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib

3 September 2018

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Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer

3 September 2018

1 reference

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Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

3 September 2018

1 reference

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TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers

3 September 2018

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The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels

3 September 2018

1 reference

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Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer.

3 September 2018

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The hypoxic response of tumors is dependent on their microenvironment.

3 September 2018

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In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

3 September 2018

1 reference

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SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo

3 September 2018

1 reference

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Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19336729

12 December 2020

inferred from PubMed ID database lookup

Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19336729

12 December 2020

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Prognostic assessment of 2,361 patients who underwent pulmonary resection for non-small cell lung cancer, stage I, II, and IIIA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19336729

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1940-6207.CAPR-08-0213

1 reference

19 August 2017

1 reference

19 August 2017

1 reference