Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors (Q37227943)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19528657%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors (English)

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31 January 2020

3

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31 January 2020

Alexei V Tepikin

5

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author name string

Julia V Gerasimenko

1

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György Lur

2

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31 January 2020

Etsuko Ebisui

4

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31 January 2020

Katsuhiko Mikoshiba

6

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Oleg V Gerasimenko

7

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31 January 2020

Ole H Petersen

8

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language of work or name

English

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publication date

15 June 2009

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Proceedings of the National Academy of Sciences of the United States of America

31 January 2020

published in

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31 January 2020

volume

106

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issue

26

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page(s)

10758-10763

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Fatty acids, alcohol and fatty acid ethyl esters: toxic Ca2+ signal generation and pancreatitis

31 January 2020

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6 September 2017

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Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites

6 September 2017

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ATP-independent luminal oscillations and release of Ca2+ and H+ from mast cell secretory granules: implications for signal transduction

6 September 2017

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NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

6 September 2017

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An examination of the secretion-like coupling model for the activation of the Ca2+ release-activated Ca2+ current I(CRAC) in RBL-1 cells

6 September 2017

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Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells

6 September 2017

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Calcium signaling and acute pancreatitis: specific response to a promiscuous messenger

6 September 2017

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Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

6 September 2017

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Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells

6 September 2017

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The pharmacology of intracellular Ca(2+)-release channels

14 September 2017

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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

14 September 2017

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Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells.

28 September 2017

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NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area.

26 June 2018

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The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis.

26 June 2018

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26 June 2018

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2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca2+ release.

26 June 2018

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Phospholipase C inhibitor, U73122, releases intracellular Ca2+, potentiates Ins(1,4,5)P3-mediated Ca2+ release and directly activates ion channels in mouse pancreatic acinar cells

26 June 2018

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Presence of nonoxidative ethanol metabolism in human organs commonly damaged by ethanol abuse.

26 June 2018

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Enhanced susceptibility to pancreatitis in severe hypertriglyceridaemic lipoprotein lipase-deficient mice and agonist-like function of pancreatic lipase in pancreatic cells.

26 June 2018

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Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis

3 September 2018

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Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis

3 September 2018

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3 September 2018

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NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors

3 September 2018

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The distribution of the endoplasmic reticulum in living pancreatic acinar cells.

3 September 2018

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Receptor-activated cytoplasmic Ca2+ spiking mediated by inositol trisphosphate is due to Ca2(+)-induced Ca2+ release

3 September 2018

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12 December 2020

U73122 inhibits Ca2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells

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12 December 2020

Inositol trisphosphate and cyclic ADP-ribose-mediated release of Ca2+ from single isolated pancreatic zymogen granules

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12 December 2020

Changes in element concentrations induced by agonist in pig pancreatic acinar cells

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12 December 2020

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

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12 December 2020

Direct detection of premature protease activation in living pancreatic acinar cells

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12 December 2020

Role of Ca2+/K+ ion exchange in intracellular storage and release of Ca2+

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12 December 2020

Generation of specific Ca(2+) signals from Ca(2+) stores and endocytosis by differential coupling to messengers

1 reference

12 December 2020

Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0904818106

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31 January 2020

0 references

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31 January 2020

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