Finding a better drug for epilepsy: antiepileptogenesis targets. (Q37232240)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23061663%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Finding a better drug for epilepsy: antiepileptogenesis targets (English)

1 reference

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10 March 2020

2

1 reference

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10 March 2020

Heidrun Potschka

6

1 reference

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10 March 2020

Michele Simonato

9

1 reference

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10 March 2020

11

Astrid Nehlig

1 reference

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10 March 2020

10

Asla Pitkänen

1 reference

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10 March 2020

author name string

Katja Kobow

1

1 reference

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10 March 2020

Frances Jensen

3

1 reference

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10 March 2020

Wolfgang Löscher

4

1 reference

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10 March 2020

Istvan Mody

5

1 reference

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10 March 2020

David Prince

7

1 reference

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10 March 2020

Alejandra Sierra

8

1 reference

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10 March 2020

Jong M Rho

12

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10 March 2020

publication date

12 October 2012

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10 March 2020

1 reference

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10 March 2020

volume

53

1 reference

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10 March 2020

issue

11

1 reference

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10 March 2020

page(s)

1868-1876

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The ketogenic diet as a treatment paradigm for diverse neurological disorders

10 March 2020

cites work

1 reference

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Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons

9 September 2017

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Is it safe to use a diuretic to treat seizures early in development ?

9 September 2017

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Modulation of oxidative stress and mitochondrial function by the ketogenic diet

9 September 2017

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Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy

9 September 2017

1 reference

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Fatty acid oxidation and epilepsy.

9 September 2017

1 reference

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Altered GABA signaling in early life epilepsies

9 September 2017

1 reference

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Erythropoietin, erythropoiesis and beyond

9 September 2017

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The methylation hypothesis: do epigenetic chromatin modifications play a role in epileptogenesis?

9 September 2017

1 reference

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A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors

9 September 2017

1 reference

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A ketogenic diet reduces long-term potentiation in the dentate gyrus of freely behaving rats

9 September 2017

1 reference

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Targets for preventing epilepsy following cortical injury

9 September 2017

1 reference

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Mechanisms of epileptogenesis and potential treatment targets

9 September 2017

1 reference

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Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures.

9 September 2017

1 reference

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Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research

9 September 2017

1 reference

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Blocking early GABA depolarization with bumetanide results in permanent alterations in cortical circuits and sensorimotor gating deficits

9 September 2017

1 reference

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Polyunsaturated fatty acids and epilepsy

9 September 2017

1 reference

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Brain function and chromatin plasticity

9 September 2017

1 reference

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Altered histone acetylation is associated with age-dependent memory impairment in mice.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Epilepsy following cortical injury: cellular and molecular mechanisms as targets for potential prophylaxis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Epigenetics and the nervous system

9 September 2017

1 reference

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The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

9 September 2017

1 reference

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Roles of the cation-chloride cotransporters in neurological disease.

9 September 2017

1 reference

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Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures

9 September 2017

1 reference

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Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies.

9 September 2017

1 reference

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Synaptic integration and plasticity of new neurons in the adult hippocampus

9 September 2017

1 reference

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Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures

9 September 2017

1 reference

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Progress in neuroprotective strategies for preventing epilepsy.

9 September 2017

1 reference

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Epileptogenesis in experimental models.

9 September 2017

1 reference

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Anticonvulsant, antiepileptogenic, and antiictogenic pharmacostrategies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Angels and demons: neurotrophic factors and epilepsy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Principles of diffusion tensor imaging and its applications to basic neuroscience research

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Neuroprotective and disease-modifying effects of the ketogenic diet

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Storage of spatial information by the maintenance mechanism of LTP

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Learning induces long-term potentiation in the hippocampus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

NKCC1 transporter facilitates seizures in the developing brain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Looking into the functional architecture of the brain with diffusion MRI.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Applications of diffusion-weighted and diffusion tensor MRI to white matter diseases - a review

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

The basis of anisotropic water diffusion in the nervous system - a technical review

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Drug-mediated neuroprotection and antiepileptogenesis: animal data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Animal models of epileptogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Mesial temporal lobe epilepsy: what have we learned?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Oral administration of docosahexaenoic acid/eicosapentaeinoic acids is not anticonvulsant in rats: implications for translational research

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

A ketogenic diet does not impair rat behavior or long-term potentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

The developmental stage of dentate granule cells dictates their contribution to seizure-induced plasticity.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Inhibitory function in two models of chronic epileptogenesis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Bystander effect on brain tissue of mesoangioblasts producing neurotrophins.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketogenic diet protects against epileptogenesis as well as neuronal loss in amygdaloid-kindling seizures

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

The erythropoietin-derived peptide mimetic pHBSP affects cellular and cognitive consequences in a rat post-status epilepticus model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketogenic diet does not change NKCC1 and KCC2 expression in rat hippocampus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium-pilocarpine model of mesial temporal lobe epilepsy in adult rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Diffusion tensor MRI of axonal plasticity in the rat hippocampus

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketogenic diet does not disturb neurogenesis in the dentate gyrus in rats.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Effects of the ketogenic diet on neurogenesis after kainic acid-induced seizures in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Histone modifications in kainate-induced status epilepticus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

The ketogenic diet increases mitochondrial uncoupling protein levels and activity.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5011430

3 September 2018

1 reference

12 December 2020

Neurogenesis in the adult hippocampus

1 reference

PubMed

12 December 2020

The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis

1 reference

PubMed

12 December 2020

Diffusion tensor MRI with tract-based spatial statistics and histology reveals undiscovered lesioned areas in kainate model of epilepsy in rat

1 reference

PubMed

12 December 2020

10.1111/J.1528-1167.2012.03716.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23061663%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23061663%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23061663%20AND%20SRC:MED&resulttype=core&format=json