Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation. (Q37235009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation (English)

1 reference

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1 February 2020

0 references

1

1 reference

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1 February 2020

Stefania Ciafrè

3

1 reference

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1 February 2020

Delio Mercanti

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

R Marolda

2

1 reference

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1 February 2020

M T Ciotti

4

1 reference

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1 February 2020

P Calissano

6

1 reference

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1 February 2020

language of work or name

English

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publication date

19 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

106

1 reference

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1 February 2020

issue

27

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1 February 2020

page(s)

11358-11363

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

Apoptosis and in vitro Alzheimer disease neuronal models.

1 February 2020

cites work

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NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons.

6 September 2017

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Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases

6 September 2017

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6 September 2017

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Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?

6 September 2017

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Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?

6 September 2017

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An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

6 September 2017

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Cdk5 deregulation in the pathogenesis of Alzheimer's disease

6 September 2017

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Trk receptors: roles in neuronal signal transduction

6 September 2017

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Neurotrophin signaling through the p75 neurotrophin receptor

6 September 2017

1 reference

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Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

6 September 2017

1 reference

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Activation of Trk neurotrophin receptors in the absence of neurotrophins

6 September 2017

1 reference

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Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

6 September 2017

1 reference

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K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

6 September 2017

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Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

6 September 2017

1 reference

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Activation of the amyloidogenic route by NGF deprivation induces apoptotic death in PC12 cells

14 September 2017

1 reference

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A role for Fyn in Trk receptor transactivation by G-protein-coupled receptor signaling

14 September 2017

1 reference

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Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease

14 September 2017

1 reference

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p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells

14 September 2017

1 reference

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PI3K: downstream AKTion blocks apoptosis

28 September 2017

1 reference

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Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

28 September 2017

1 reference

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Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

26 June 2018

1 reference

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Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease

26 June 2018

1 reference

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Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

26 June 2018

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TrkA pathway activation induced by amyloid-beta (Abeta).

3 September 2018

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TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain

3 September 2018

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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

3 September 2018

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A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

3 September 2018

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Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.

3 September 2018

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HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion.

3 September 2018

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Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles.

3 September 2018

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Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

3 September 2018

1 reference

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Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

3 September 2018

1 reference

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Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699376

p75 Co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699376

Regional levels of brain phospholipase Cgamma in Alzheimer's disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699376

Functional cooperation between TrkA and p75(NTR) accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699376

Detecting changes in real-world objects: The relationship between visual long-term memory and change blindness

20 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0904998106

Development of a method for measuring cell number: Application to CNS primary neuronal cultures

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19549834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0904998106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549834%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

19549834

1 reference