The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy (Q37236249)

19 August 2017

The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy (English)

1 reference

19 August 2017

1 reference

Paola Sebastiani

3

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author name string

Chiara Gerhardinger

1

1 reference

19 August 2017

Zeina Dagher

2

1 reference

19 August 2017

Yong Seek Park

4

1 reference

19 August 2017

Mara Lorenzi

5

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19 August 2017

language of work or name

English

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publication date

28 April 2009

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19 August 2017

9

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inferred from page(s)

published in

Diabetes

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19 August 2017

58

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19 August 2017

7

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19 August 2017

1659-1667

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

19 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects

6 September 2017

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Aldose reductase in diabetic microvascular complications

6 September 2017

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Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications

6 September 2017

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Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action

6 September 2017

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New insights into TGF-beta-Smad signalling

6 September 2017

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Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein

6 September 2017

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6 September 2017

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Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment

6 September 2017

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VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

6 September 2017

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Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4

6 September 2017

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Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress

6 September 2017

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6 September 2017

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6 September 2017

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TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

6 September 2017

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Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin

6 September 2017

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6 September 2017

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AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-beta1 promoter in mesangial cells.

6 September 2017

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

6 September 2017

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Identification of a series of transforming growth factor beta-responsive genes by retrovirus-mediated gene trap screening

6 September 2017

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Expression of vascular endothelial growth factor in the human retina and in nonproliferative diabetic retinopathy.

6 September 2017

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Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy

6 September 2017

1 reference

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Increased expression of basement membrane collagen in human diabetic retinopathy

6 September 2017

1 reference

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Diabetic retinopathy. A clinical overview

6 September 2017

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SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model

6 September 2017

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14 September 2017

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14 September 2017

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Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells

14 September 2017

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Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

IGF-I mRNA and signaling in the diabetic retina

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Differential gene expression in pulmonary artery endothelial cells exposed to sickle cell plasma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Expression of acute-phase response proteins in retinal Müller cells in diabetes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Syndecan-2 regulates transforming growth factor-beta signaling.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Oncofetal fibronectin in diabetic retinopathy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699853

Müller cell changes in human diabetic retinopathy

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19401417

12 December 2020

inferred from PubMed ID database lookup

An aldose reductase inhibitor prevents glucose-induced increase in transforming growth factor-beta and protein kinase C activity in cultured mesangial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19401417

12 December 2020

inferred from PubMed ID database lookup

Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19401417

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.2337/DB08-1008

1 reference

19 August 2017

1 reference

19 August 2017

1 reference