STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. (Q37236401)

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22 February 2020

title

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease (English)

1 reference

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22 February 2020

main subject

apoptotic process

0 references

endoplasmic reticulum

1 reference

based on heuristic

inferred from title

author

Arvin Iracheta-Vellve

2

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22 February 2020

author name string

Jan Petrasek

1

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22 February 2020

Timea Csak

3

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22 February 2020

Abhishek Satishchandran

4

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22 February 2020

Karen Kodys

5

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22 February 2020

Evelyn A Kurt-Jones

6

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22 February 2020

Katherine A Fitzgerald

7

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22 February 2020

Gyongyi Szabo

8

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22 February 2020

language of work or name

English

0 references

publication date

19 September 2013

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

22 February 2020

published in

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22 February 2020

volume

110

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22 February 2020

issue

41

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22 February 2020

page(s)

16544-16549

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

22 February 2020

cites work

1 reference

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IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

6 September 2017

1 reference

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STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

6 September 2017

1 reference

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Alcoholic liver disease: pathogenesis and new therapeutic targets

6 September 2017

1 reference

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Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.

6 September 2017

1 reference

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Pathogen recognition by the innate immune system

6 September 2017

1 reference

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Viral apoptosis is induced by IRF-3-mediated activation of Bax

6 September 2017

1 reference

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An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice.

6 September 2017

1 reference

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

6 September 2017

1 reference

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

6 September 2017

1 reference

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TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol

6 September 2017

1 reference

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Regulation of hepatic lipogenesis by the transcription factor XBP1

6 September 2017

1 reference

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CYP2E1 and oxidative liver injury by alcohol

6 September 2017

1 reference

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Triggering the innate antiviral response through IRF-3 activation

6 September 2017

1 reference

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Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799324

Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice

6 September 2017

1 reference

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The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799324

Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799324

3 September 2018

Identifiers

DOI

10.1073/PNAS.1308331110

1 reference

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22 February 2020

0 references

1 reference

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22 February 2020

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