The relevance of mouse models to understanding the development and progression of human breast cancer (Q37243959)

19 August 2017

1 reference

title

The relevance of mouse models to understanding the development and progression of human breast cancer (English)

1 reference

19 August 2017

1 reference

D Craig Allred

1

1 reference

PubMed ID

18704660

19 August 2017

Daniel Medina

series ordinal

2

1 reference

PubMed ID

18704660

19 August 2017

language of work or name

1 reference

14 August 2008

1 reference

Journal of Mammary Gland Biology and Neoplasia

19 August 2017

1 reference

19 August 2017

13

1 reference

19 August 2017

3

1 reference

19 August 2017

279-288

1 reference

https://scigraph.springernature.com/pub.10.1007/s10911-008-9093-5

19 August 2017

0 references

cites work

RCAS-TVA in the mammary gland: an in vivo oncogene screen and a high fidelity model for breast transformation?

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-008-9093-5

Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-008-9093-5

Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-008-9093-5

Genetically engineered mouse models of mammary intraepithelial neoplasia

21 January 2018

1 reference

12 December 2020

Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer.

1 reference

12 December 2020

Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens

1 reference

12 December 2020

Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

1 reference

12 December 2020

Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model

1 reference

12 December 2020

Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model.

1 reference

12 December 2020

Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.

1 reference

12 December 2020

Hormone-induced chromosomal instability in p53-null mammary epithelium

1 reference

12 December 2020

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

1 reference

12 December 2020

Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways

1 reference

12 December 2020

Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.

1 reference

12 December 2020

Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial

1 reference

12 December 2020

Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis

1 reference

12 December 2020

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer

1 reference

12 December 2020

Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes

1 reference

12 December 2020

Transgenic Polyoma middle-T mice model premalignant mammary disease

1 reference

12 December 2020

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice

1 reference

12 December 2020

Molecular portraits of human breast tumours

1 reference

12 December 2020

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

1 reference

12 December 2020

Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth

1 reference

12 December 2020

Estrogen promotes mammary tumor development in C3(1)/SV40 large T-antigen transgenic mice: paradoxical loss of estrogen receptoralpha expression during tumor progression

1 reference

12 December 2020

Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu

1 reference

12 December 2020

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

1 reference

12 December 2020

Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling

1 reference

12 December 2020

An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions

1 reference

12 December 2020

Reconstruction of functionally normal and malignant human breast tissues in mice

1 reference

12 December 2020

Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice

1 reference

12 December 2020

Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ.

1 reference

12 December 2020

Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation

1 reference

12 December 2020

Hormone-Dependent Mammary Tumors in Strain GR/A Mice. IV. Origin and Progression 2

1 reference

12 December 2020

FOXA1 Expression in Breast Cancer Correlation with Luminal Subtype A and Survival

1 reference

12 December 2020

Mutation of the murine Bloom's syndrome gene produces global genome destabilization

1 reference

12 December 2020

Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor

1 reference

12 December 2020

Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.

1 reference

12 December 2020

Progesterone induction of mammary carcinomas in BALB/c female mice. Correlation between progestin dependence and morphology

1 reference

12 December 2020

Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ

1 reference

12 December 2020

EMT tumorigenesis in the mouse mammary gland

1 reference

12 December 2020

Repeated observation of breast tumor subtypes in independent gene expression data sets

1 reference

12 December 2020

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

1 reference

12 December 2020

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

1 reference

12 December 2020

Tamoxifen inhibition of estrogen receptor-alpha-negative mouse mammary tumorigenesis

1 reference

12 December 2020

Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

1 reference

12 December 2020

A role of estrogen/ERalpha signaling in BRCA1-associated tissue-specific tumor formation

1 reference

12 December 2020

COX-2 inhibitor celecoxib suppresses tumor growth and lung metastasis of a murine mammary cancer.

1 reference

12 December 2020

Role of infiltrated leucocytes in tumour growth and spread

1 reference

12 December 2020

A novel orthotopic model of breast cancer metastasis to bone.

1 reference

12 December 2020

Tumor-associated macrophages press the angiogenic switch in breast cancer.

1 reference

12 December 2020

Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis

1 reference

12 December 2020

Ras activation in human breast cancer

1 reference

12 December 2020

From mice to humans: identification of commonly deregulated genes in mammary cancer via comparative SAGE studies

1 reference

12 December 2020

Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist

1 reference

12 December 2020

Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells

1 reference

12 December 2020

Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

1 reference

12 December 2020

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

12 December 2020

Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes.

1 reference

12 December 2020

A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland

1 reference

12 December 2020

The Rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice

1 reference

12 December 2020

Classification of ductal carcinoma in situ by gene expression profiling

1 reference

12 December 2020

Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail

1 reference

12 December 2020

Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer

1 reference

12 December 2020

Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis

1 reference

12 December 2020

Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors

1 reference

12 December 2020

Hormone-dependent mammary tumors in strain GR-A mice. I. Alternation between ductal and tumorous phases of growth during serial transplantation

1 reference

12 December 2020

Special considerations in mouse models of breast cancer.

1 reference

12 December 2020

On the origin and progression of ductal carcinoma in the human breast

1 reference

12 December 2020

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

12 December 2020

The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice

1 reference

12 December 2020

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1 reference

12 December 2020

Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer

1 reference

12 December 2020

Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis

1 reference

12 December 2020

Biological and genetic properties of the p53 null preneoplastic mammary epithelium

1 reference

12 December 2020

Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution

1 reference

12 December 2020

A gene-expression signature as a predictor of survival in breast cancer

1 reference

12 December 2020

A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development

1 reference

12 December 2020

Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss

1 reference

12 December 2020

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

1 reference

12 December 2020

Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis

1 reference

12 December 2020

Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

1 reference

12 December 2020

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

1 reference

12 December 2020

Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells

1 reference

12 December 2020

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

12 December 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

12 December 2020

1 reference

12 December 2020

The transcriptional repressor Snail promotes mammary tumor recurrence

1 reference

12 December 2020

Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype

1 reference

12 December 2020

Epithelial-mesenchymal transitions in tumour progression

1 reference

12 December 2020

Heterogeneity of mammary lesions represent molecular differences

1 reference

12 December 2020

10.1007/S10911-008-9093-5

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18704660